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A customizable multiplex protein microarray for antibody testing and its application for tick-borne and other infectious diseases.
Sci Rep
January 2025
Vibrant Sciences LLC., San Carlos, CA, USA.
Tick-borne infections are the most common vector-borne diseases in the USA. Ticks harbor and transmit several infections with Lyme disease being the most common tickborne infection in the US and Europe. Lack of awareness about tick populations, specific diagnostic tests, and overlapping signs and symptoms of tick-borne infections can often lead to misdiagnosis affecting treatment and the prevalence data reported especially for non-Lyme tick-borne infections.
View Article and Find Full Text PDFPrevalence of Powassan Virus Seropositivity Among People with History of Lyme Disease and Non-Lyme Community Controls in the Northeastern United States.
Vector Borne Zoonotic Dis
April 2024
Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York, USA.
Article Synopsis
- Lyme disease affects approximately 476,000 people annually in the U.S., presenting symptoms like rash and flu-like feelings, with varied outcomes that are not yet understood.
- The study aimed to assess the presence of Powassan virus (POWV) antibodies in individuals with a history of Lyme disease, comparing those with low and high antibody levels.
- Results showed discrepancies between antibody tests and no significant clinical symptom differences based on antibody levels, indicating challenges in diagnosing flavivirus exposure and highlighting the need for further research on potential co-infections.
Bacteremia in Patients With Fever and Acute Lower Extremity Pain in a Non-Lyme Endemic Region.
Pediatrics
January 2024
Connecticut Children's Hospital, Hartford, Connecticut.
Identifying Potential Lyme Disease Cases Using Self-Reported Worldwide Tweets: Deep Learning Modeling Approach Enhanced With Sentimental Words Through Emojis.
J Med Internet Res
October 2023
Département de médecine sociale et préventive, École de Santé Publique de l'Université de Montréal, Université de Montréal, Montréal, QC, Canada.
Background: Lyme disease is among the most reported tick-borne diseases worldwide, making it a major ongoing public health concern. An effective Lyme disease case reporting system depends on timely diagnosis and reporting by health care professionals, and accurate laboratory testing and interpretation for clinical diagnosis validation. A lack of these can lead to delayed diagnosis and treatment, which can exacerbate the severity of Lyme disease symptoms.
View Article and Find Full Text PDFIntroduction: Considering increasing rates of tick-borne diseases (TBDs) in the United States, we investigated the scope of continuing medical education (CME) available to physicians on these infections.
Methods: We surveyed online medical board and society databases serving front-line primary and emergency/urgent care providers for the availability of TBD-specific CME between March 2022 and June 2022. We recorded and analyzed opportunity title, author, web address, publication year, learning objectives, CME credit values, and CME credit type.
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