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http://dx.doi.org/10.1111/j.1398-9995.2005.00648.x | DOI Listing |
Masui
October 2010
Department of Anesthesiology and Pain Medicine, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo 136-0075.
A healthy 29-year-old woman received epidural block for severe lumbago in an outpatient clinic. Fifteen minutes after injection of mepivacaine 0.5% with dexamethasone into the epidural space, the patient complained of itching of eyelids followed by generalized pruritus.
View Article and Find Full Text PDFAllergy Asthma Immunol Res
October 2009
Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, Korea.
Hyaluronidase is a goat testicular protein that hydrolyzes hyaluronic acid, a structural component of the intercellular matrix. It is commonly used as a spreading factor to improve the diffusion of drugs, including local anesthetics and chemotherapeutics. We experienced a 55-yr-old female with generalized urticaria that developed within 1 hr after the epidural injection of hyaluronidase.
View Article and Find Full Text PDFJ Investig Allergol Clin Immunol
December 2006
Sección Alergia, Hospital General de Alicante, Aliccante, Spain.
Among the various adverse reactions to local anesthetics, IgE-mediated reactions, particularly to the more commonly used amide group, are extremely rare. We report the case of a 39-year-old man who suffered itching and generalized urticaria with facial angioedema 15 minutes after administration of mepivacaine. Skin tests revealed a strong positive reaction to mepivacaine, lidocaine, and ropivacaine, but negative reactions to bupivacaine and levobupivacaine.
View Article and Find Full Text PDFAllergy
February 2005
Servicio de Alergia, Hospital General Universitario Gregorio, Marañón, C/Dr. Esquerdo, 46, 28007 Madrid, Spain.
Ann Pharmacother
January 1996
University Hospital Infanta Cristina, Badajoz, Spain.
Objective: To report a patient with an anaphylactic reaction related to povidone administration.
Case Summary: A 37-year-old man with a history of allergic rhinitis presented with urticaria, dyspnea, wheezing, rhinorrhea, and dysphonia 20 minutes after the intraarticular administration of mepivacaine hydrochloride and paramethasone acetate in his right knee. Two months after this episode, he was admitted for controlled provocation tests.
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