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Increased respiratory syncytial virus-associated hospitalizations and ambulatory visits in very preterm infants in the first year of life following discontinuation of access to palivizumab.
Am J Perinatol
January 2025
Pediatrics, Dalhousie University, Halifax, Canada.
Background: From 2002 to 2023, palivizumab was the only intervention to reduce RSV-associated hospitalizations in high-risk infants in Canada, but advances in RSV prevention are drastically changing this landscape. Eligibility criteria for this monoclonal antibody for preterm infants varied over time across each of 10 Canadian provinces and 3 territories. The national professional pediatric association (Canadian Paediatric Society) revised its eligibility recommendations in 2015, removing access for preterm infants 30 to 32 weeks gestation (WG).
View Article and Find Full Text PDFEvaluating ADHD medication trial representativeness: a Swedish population-based study comparing hypothetically trial-eligible and trial-ineligible individuals.
Lancet Psychiatry
January 2025
Developmental Evidence synthesis, Prediction, Implementation lab, Centre for Innovation in Mental Health, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK; Hampshire and Isle of Wight NHS Foundation Trust, Southampton, UK; Clinical and Experimental Sciences (CNS and Psychiatry), Faculty of Medicine, University of Southampton, Southampton, UK; Hassenfeld Children's Hospital at NYU Langone, New York University Child Study Center, New York City, NY, USA; DiMePRe-J-Department of Precision and Regenerative Medicine-Jonic Area, University of Bari Aldo Moro, Bari, Italy.
Background: Randomised controlled trials (RCTs) evaluating ADHD medications often use strict eligibility criteria, potentially limiting generalisability to patients in real-world clinical settings. We aimed to identify the proportion of individuals with ADHD who would be ineligible for medication RCTs and evaluate differences in treatment patterns and clinical and functional outcomes between RCT-eligible and RCT-ineligible individuals.
Methods: We used multiple Swedish national registries to identify individuals with ADHD, aged at least 4 years at the age of diagnosis, initiating pharmacological treatment between Jan 1, 2007, and Dec 31, 2019, with follow-up up to Dec 31, 2020.
Hydrology and water quality evaluation for potential HABs under future climate scenarios.
J Environ Manage
January 2025
Department of Agricultural and Biological Engineering, Mississippi State University, Mississippi State, MS, 39762, United States. Electronic address:
Harmful algal blooms (HABs) are increasingly a global concern and the issue of all fifty states in the U.S as it poses a threat to human health and aquatic ecosystem. This study aimed to investigate the relationship of HABs with streamflow and water quality parameters and assess the hydrology-based potential future HABs in the Ohio River Basin at Ironton (ORBI) using the Soil and Water Assessment Tool (SWAT).
View Article and Find Full Text PDFThe moderating effect of weight loss intentions on dynamic associations between weight suppression and disordered eating.
Eat Behav
January 2025
Department of Psychology, University of Western Ontario, Canada. Electronic address:
Objective: Weight suppression refers to the difference between one's current and highest previous weight in adulthood and has been associated with development of eating pathology. Previous research has been agnostic as to whether reported weight suppression reflects deliberate weight control behavior, and few studies have assessed whether weight loss that occurs unintentionally (e.g.
View Article and Find Full Text PDFOn the occurrence, behaviour, and fate of naphthenic acid fraction compounds in aquatic environments.
Sci Total Environ
January 2025
Department of Civil, Geological and Environmental Engineering, University of Saskatchewan, 57 Campus Dr, Saskatoon, Saskatchewan S7N 5A9, Canada; University of Lethbridge, Office of the Vice President (Research), Lethbridge, Alberta, Canada. Electronic address:
Naphthenic acids and naphthenic acid fraction compounds (NAFCs) are associated with production of unconventional petroleum resources, especially the Athabasca Oil Sands of Alberta, Canada. This complex mixture of acidic organic compounds is toxic to a variety of taxa, and so represents an important environmental management challenge. Thus, there is clear motivation to better understand the occurrence and characteristics of NAFCs in aquatic environments, their chemical behaviour, and environmental fate.
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