The potentialities of optimizing the clinical use of electric surface properties of erythrocyte blood samples were investigated. The ordinarily used parameter of the eletrokinetic erythrocyte potential based on the mean value of electrophoretic mobility was shown to be inaccurate and low informative. Asymmetry factor and erythrogram excess (distribution parameters) are recommended for use to enhance the adequate evaluation of changes in the above parameter and to make it diagnostically more effective. Principles of interpretation of changes' results are described.

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