Byssochlamys nivea as a source of mycophenolic acid.

Appl Environ Microbiol

Laboratoire de Pharmacologie-Toxicologie, Institut National de la Recherche Agronomique, 180 chemin de Tournefeuille, 31931 Toulouse Cedex 9, France.

Published: January 2005

AI Article Synopsis

  • Byssochlamys species can spoil fruits and silages and produce the harmful mycotoxin patulin.
  • Researchers studied the production of secondary metabolites by Byssochlamys nivea.
  • They found mycophenolic acid and its precursors, 5-methylorsellinic acid and 5,7-dihydroxy-4-methylphthalide, in all examined B. nivea strains.

Article Abstract

Byssochlamys species are responsible for spoilage and degradation of fruits and silages and can also produce the mycotoxin patulin. We analyzed secondary metabolite production by Byssochlamys nivea. Mycophenolic acid and its precursors, 5-methylorsellinic acid and 5,7-dihydroxy-4-methylphthalide, were identified in all of the B. nivea strains that we examined.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC544229PMC
http://dx.doi.org/10.1128/AEM.71.1.550-553.2005DOI Listing

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