Melatonin exerts its biological effects through pharmacological specific, high affinity G protein-coupled receptors. This review introduced the structure, function, and regulation of melatonin receptor,the cloning and structure, developmental expression, mapping and polymorphism of melatonin receptor gene. The relationship between melatonin receptor gene and reproductive seasonality was also discussed.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Integration of Phytomelatonin Signaling With Jasmonic Acid in Wound-induced Adventitious Root Regeneration.
Adv Sci (Weinh)
January 2025
College of Horticulture, China Agricultural University, Beijing, 100193, China.
Plants exhibit remarkable regenerative abilities under stress conditions like injury, herbivory, and damage from harsh weather, particularly through adventitious root formation. They have sophisticated molecular mechanisms to recognize and respond to wounding. Jasmonic acid (JA), a wound hormone, triggers auxin synthesis to stimulate root regeneration.
View Article and Find Full Text PDFEngineered Extracellular Vesicles Modified by Angiopep-2 Peptide Promote Targeted Repair of Spinal Cord Injury and Brain Inflammation.
ACS Nano
January 2025
Department of Orthopedics, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing 210000 Jiangsu, China.
Engineered extracellular vesicles play an increasingly important role in the treatment of spinal cord injury. In order to prepare more effective engineered extracellular vesicles, we biologically modified M2 microglia. Angiopep-2 (Ang2) is an oligopeptide that can target the blood-brain barrier.
View Article and Find Full Text PDFMulti-ancestry genome-wide association analyses: a comparison of meta- and mega-analyses in the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study.
BMC Genomics
January 2025
Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Background: There is increasing need for effective incorporation of high-dimensional genetics data from individuals with varied ancestry in genome-wide association (GWAS) analyses. Classically, multi-ancestry GWAS analyses are performed using statistical meta-analysis to combine results conducted within homogeneous ancestry groups. The emergence of cosmopolitan reference panels makes collective preprocessing of GWAS data possible, but impact on downstream GWAS results in a mega-analysis framework merits investigation.
View Article and Find Full Text PDFEffects of melatonin on planaria head regeneration are dependent on both timing and duration of exposure.
Physiol Rep
January 2025
Department of Biology, Slippery Rock University of Pennsylvania, Slippery Rock, Pennsylvania, USA.
Melatonin is a multifunctional biomolecule with demonstrated stimulatory, inhibitory, and antioxidant effects, including both receptor-mediated and receptor-independent mechanisms of action. One of its more perplexing effects is the disruption of regeneration in planaria. Head regeneration in planaria is a remarkable phenomenon in which stem cells (neoblasts) migrate to the wound site, proliferate, then differentiate into all functional tissue types within days of injury.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!