[Measurement of uric acid of seminal plasma in fertile and infertile males].

Zhonghua Nan Ke Xue

Laboratory of Reproduction & Genetics, Nanjing General Hospital of Nanjing Command, PLA, Nanjing, Jiangsu 210002, China.

Published: December 2004

AI Article Synopsis

  • The study aimed to measure uric acid levels in the seminal plasma of both fertile and infertile males.
  • The research included 163 infertile males, categorized into various groups based on their condition, and compared their uric acid concentrations to a control group of 20 fertile men using advanced analysis techniques.
  • Results showed that fertile males had significantly higher uric acid levels than the infertile groups, suggesting that uric acid could be important for male reproduction due to its antioxidant properties.

Article Abstract

Objective: To measure uric acid of seminal plasma in fertile and infertile males.

Methods: One hundred and sixty-three infertile males were divided into an obstructive azoospermic group (15 cases), a non-obstructive azoospermic group (36 cases), an oligozoospermic group (43 cases), and an asthenozoospermic group (69 cases). Twenty fertile males were included in the control group. Uric acid concentrations of seminal plasma in the fertile and infertile men were assessed by spectrophotometer, and sperm parameters were analyzed by computer-assisted semen analysis (CASA) system.

Results: Uric acid concentration of seminal plasma in the control group was significantly higher than all the infertile groups (P < 0.01), and that of the obstructive azoospermic group significantly lower than the other infertile groups (P < 0.1), but no significant difference was observed among the other infertile groups (P > 0.05).

Conclusion: Uric acid may play an important role in male reproduction because of its antioxidative property.

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