AI Article Synopsis
- Signet ring cell lymphoma is a rare cancer that features large, clear cells and can be found in lymph nodes and other body areas, resembling mucin-producing adenocarcinoma.
- A case study details a 59-year-old male with this type of lymphoma located in the oropharyngeal mucosa, showing specific histopathological and immunophenotypic characteristics.
- Despite reviewing the literature, no similar cases were found, and the patient experienced a poor clinical outcome, passing away two months post-diagnosis without treatment.
Article Abstract
Signet ring cell lymphoma is a rare neoplasm characterized by large, vacuolated and clear cells mimicking mucin-producing adenocarcinoma. It is localized in nodal and extranodal sites. A case of a 59 years old male, with a diffuse lymphoma signet ring cell type localized on oropharyngeal mucosa is reported. The histopathology study showed signet ring cells and the immunophenotype was: vimentine(+), CD45(+), CD20(+), Ig M(+), Kappa chain(+) and high index proliferative activity of neoplastic cells (Ki 67:70%). After a review of the literature and previous reports, we could not find a similar case in this anatomic site. The patient had a unfavourable clinical course and died two months after the diagnosis without receiving any treatment.
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