Objective: To estimate the number of necessary beds for tuberculosis patients in Japan from the view point of isolation of the source of infection.
Methods: We calculated the number of necessary beds for tuberculosis cases separately for the initial phase and for the chronic excreters. For the initial phase we calculated by multiplying the number of detected tuberculosis cases and the duration of hospitalization. The number of detected cases is based on the figures in 2002 and the duration of hospitalization is assumed to be 90 days for sputum smear positive cases and 60 days for sputum smear negative cases. We calculated the number of necessary beds using the Monte Carlo simulation for each prefecture on the assumption that the incidence and the duration of diseases will be under the effect of random fluctuation with the Poisson's distribution for the number of cases and with the log normal distribution for the duration of hospitalization. We also considered the seasonal fluctuation.
Results: Our calculation revealed that around 6,413 beds would be necessary for the initial phase and 200-400 beds for chronic excreters in Japan. There are several prefectures which only requires less than 30 beds.
Discussion: Currently, Japan has around 17,000 beds secured for tuberculosis patients. Our calculation showed that this was much more than needed. In many areas, one ward will provide more than sufficient number of tuberculosis beds. Specialist consultation system must be improved because of the reduction in the number of TB cases treated at hospitals with TB wards and TB specialists. For the treatment of non-infectious TB, ambulatory DOT system, TB shelter and nursing care facilities would be necessary to guarantee compliance to treatment.
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Biomolecules
January 2025
Department of Dermatology, Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Acral melanoma is a distinct subtype of cutaneous malignant melanoma that uniquely occurs on ultraviolet (UV)-shielded, glabrous skin of the palms, soles, and nail beds. While acral melanoma only accounts for 2-3% of all melanomas, it represents the most common subtype among darker-skinned, non-Caucasian individuals. Unlike other cutaneous melanomas, acral melanoma does not arise from UV radiation exposure and is accordingly associated with a relatively low tumor mutational burden.
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January 2025
Department of General, Transplant, and Liver Surgery, Medical University of Warsaw, 02-091 Warsaw, Poland.
Liver transplantation is the only curative option for end-stage liver disease and is necessary for an increasing number of patients with advanced primary or secondary liver cancer. Many patient groups can benefit from this treatment, however the shortage of liver grafts remains an unsolved problem. Liver bioengineering offers a promising method for expanding the donor pool through the production of acellular scaffolds that can be seeded with recipient cells.
View Article and Find Full Text PDFChildren (Basel)
January 2025
Department of Pediatrics, Patras Medical School, University of Patras, University Hospital of Patras, 26504 Patras, Greece.
Background/objectives: Limited data exist on the organization and operation of Level II/III Neonatal Intensive Care Units (NICUs) in Greece; this retrospective cross-sectional survey explored their structure and functioning in 2004 and 2022.
Methods: A structured questionnaire was utilized, along with demographic and perinatal data obtained from the Hellenic Statistical Authority.
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Int J Environ Res Public Health
January 2025
Healthcare Analysis and Forecasting, Wantage OX12 0NE, UK.
This study investigates the process of planning for future inpatient resources (beds, staff and costs) for maternity (pregnancy and childbirth) services. The process of planning is approached from a patient-centered philosophy; hence, how do we discharge a suitably rested healthy mother who is fully capable of caring for the newborn baby back into the community? This demonstrates some of the difficulties in predicting future births and investigates trends in the average length of stay. While it is relatively easy to document longer-term (past) trends in births and the conditions relating to pregnancy and birth, it is exceedingly difficult to predict the future nature of such trends.
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January 2025
Frontier Nursing University, United States of America.
Over 2005-2019, the number of neonatal intensive care units (NICUs) grew by 10%, and the number of NICU beds increased by 30%. This expansion in intensive care has raised concerns over unwarranted intensive care admissions. In this study, we examine whether the greater supply of NICUs causally raises admission rates.
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