[Study on the effects of two kinds of cactus polysaccharide on erythrocyte membrane protein and fluidity of the lipid in S180 mice].

Zhongguo Zhong Yao Za Zhi

Postdoctal Research of the Institute of Materia Medica, Harbin University of Commerce, Harbin 150076, China.

Published: October 2004

Objective: To study the effects of two kinds of cactus polysaccharide on Band 3 protein, cross-linking protein and lipid fluidity of erythrocyte membrane in S180 mice.

Method: The membrane protein content was analysed by SDS-PAGE. Lipid fluidity was measured by Skinitzky method.

Result: The two kinds of cactus polysaccharide increased the content of Band 3 protein and decreased the content of cross-linking protein, raised the lipid fluidity. While the effect of median dose group of medical cactus polysaccharide is very remarkable (P < 0.01), the effect of high dose group of edible cactus polysaccharide is very remarkable (P < 0.01).

Conclusion: By improving the erythrocyte membrane function of tumor-mice, they enhanced the immune function, which may be one of anti-tumor mechanisms.

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