Objective: To study flavonoids in Scutellaria barbata and elucidate their structures.
Method: Compounds were isolated and purified by normal column chromatography, paper thin layer chromatography and Sephadex chromatography. The chemical structures were elucidated by ESI mass and NMR spectra.
Result: Five flavonoids were isolated from S. barbata and identified as apigenin (1), luteolin (2), ethyl-7-O-apigenin-glucuronate (3), apigenin-7-O-beta-glucoside (4), and apigenin-7-O-neohesperidoside (5), in addition to benzyaldehyde (6).
Conclusion: Flavonoidglycoside (3), (4) and (5) were isolated from S. barbata for the first time.
Download full-text PDF |
Source |
---|
Chem Biodivers
November 2024
State Key Laboratory of Southwestern Chinese Medicine Resources, and Innovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, P. R. China.
Five new secoiridoids, gentianopsins A-E (1-5), along with two known analogues (6 and 7) were isolated from the whole plants of the medicinal herb Gentianopsis barbata. Their structures were elucidated by a comparison of extensive spectroscopic analysis (1D and 2D NMR, and HRMS) and quantum chemical calculations. Gentianopsins A (1) and B (2) represented two unusual skeletons of trihomo-secoiridoids.
View Article and Find Full Text PDFPLoS One
October 2024
Department of Biological Sciences, Purdue University-Fort Wayne, Fort Wayne, Indiana, United States of America.
Emerging pathogenic fungi have become a topic of conservation concern due to declines observed in several host taxa. One emerging fungal pathogen, Ophidiomyces ophidiicola, is well documented as the causative agent of ophidiomycosis, otherwise known as snake fungal disease (SFD). O.
View Article and Find Full Text PDFJ Ethnopharmacol
December 2024
Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, 100010, China. Electronic address:
Ethnopharmacological Relevance: The treatment options for triple-negative breast cancer (TNBC) are limited. Traditional Chinese Medicine (TCM) plays an important role in the treatment of TNBC. The herb pair Scutellaria barbata D.
View Article and Find Full Text PDFACS Appl Bio Mater
August 2024
Department of Engineering Science, Faculty of Engineering and Architecture, İzmir Katip Çelebi University, İzmir 35620, Turkey.
The efficient removal of lead ions at low concentrations is paramount in combating the significant threat posed by water pollution resulting from industrial activities and population growth. In this study, electrospun /PAN fibers were developed to efficiently remove lead(II) ions from water. The morphology, structure, and mechanical properties of the fibers were examined, highlighting that the augmentation of the surface area through the conversion of into the polymer fibers facilitates increased metal bonding sites during sorption.
View Article and Find Full Text PDFJ Environ Sci Health C Toxicol Carcinog
January 2025
Division of Biochemical Toxicology, National Center for Toxicological Research (NCTR)/U.S. FDA, Jefferson, Arkansas, USA.
Since usnic acid was first isolated in 1844 as a prominent secondary lichen metabolite, it has been used for various purposes worldwide. Usnic acid has been claimed to possess numerous therapeutic properties, including antimicrobial, anti-inflammatory, antiviral, anti-proliferative, and antipyretic activities. Approximately two decades ago, crude extracts of usnic acid or pure usnic acid were marketed in the United States as dietary supplements for aiding in weight loss as a "fat-burner" and gained popularity in the bodybuilding community; however, hepatotoxicity was documented for some usnic acid containing products.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!