[Studies on the flavonoids in herb from Scutellaria barbata].

Zhongguo Zhong Yao Za Zhi

Key Laboratory of Bioorganic and Molecular Engineering, Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.

Published: October 2004

AI Article Synopsis

  • - The study aimed to identify and analyze the flavonoids present in the plant Scutellaria barbata.
  • - Researchers used various chromatography techniques and mass/NMR spectroscopy to isolate and clarify the structures of the compounds.
  • - Five flavonoids were successfully identified, with three of them being reported as isolated for the first time from this plant species.

Article Abstract

Objective: To study flavonoids in Scutellaria barbata and elucidate their structures.

Method: Compounds were isolated and purified by normal column chromatography, paper thin layer chromatography and Sephadex chromatography. The chemical structures were elucidated by ESI mass and NMR spectra.

Result: Five flavonoids were isolated from S. barbata and identified as apigenin (1), luteolin (2), ethyl-7-O-apigenin-glucuronate (3), apigenin-7-O-beta-glucoside (4), and apigenin-7-O-neohesperidoside (5), in addition to benzyaldehyde (6).

Conclusion: Flavonoidglycoside (3), (4) and (5) were isolated from S. barbata for the first time.

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