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Inhibition of pterygium cell fibrosis by the Rho kinase inhibitor.
Sci Rep
December 2024
Eugene and Marilyn Glick Eye Institute, Indiana University School of Medicine, RM305v, 1160 W. Michigan St., Indianapolis, IN, 46202, USA.
Pterygium is an ocular disease in which the conjunctival tissue invades the cornea. When the pterygium tissue reaches the pupillary region, the visual function of the patient is affected. Currently, surgical removal is the only effective treatment.
View Article and Find Full Text PDFArticle Synopsis
- Ophthalmic diseases, commonly affecting the elderly, often go untreated due to limited resources and decreased daily activities, highlighting the need for better eye care, especially in home settings.
- A study was conducted on Miyako Island, Japan, using portable equipment to examine 147 home-based patients, revealing various eye conditions, particularly cataracts, with over half of those affected not having undergone surgery.
- The findings emphasize the importance of improving eye care systems in remote areas to prevent complications like glaucoma and ensure better access to treatment for elderly patients.
Duration of Bare Sclera Pterygium Surgery Combined with Mitomycin C with and Without Tranexamic Acid: A Randomized Double-Blind Controlled Trial.
J Ocul Pharmacol Ther
December 2024
Department of Ophthalmology, Rambam Health Care Campus, Haifa, Israel.
Article Synopsis
- The study aimed to assess the effectiveness of subconjunctival tranexamic acid (TXA) in reducing bleeding, shortening surgery time, and enhancing recovery in pterygium surgery through a double-blind, randomized controlled trial involving 50 patients.
- Results showed no significant differences between the TXA group and the saline control group in terms of surgery duration, intraoperative bleeding, or postoperative visual acuity, with both groups faring similarly in all main outcome measures.
- Although the use of TXA was deemed safe with no adverse effects, the findings suggest that it does not provide substantial benefits in improving surgical outcomes for pterygium surgery, indicating a need for further research on alternative treatments or surgical techniques.
Association between ocular diseases and screen time and sedentary time derived from job-exposure matrices.
Sci Rep
November 2024
Department of Preventive Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara-shi, Kanagawa, 259-1193, Japan.
After developing job-exposure matrices (JEMs) for screen and sedentary time, we aimed to assess the associations between the JEM-derived exposures and various ocular diseases. We collected data from patients hospitalized from 2005 to 2021. JEMs were developed from 41,718 patients with occupational information and screen and sedentary times.
View Article and Find Full Text PDFThe relationship between contact lens ultraviolet light transmittance and myopia progression: a large-scale retrospective cohort study.
Precis Clin Med
December 2024
Department of Ophthalmology and Visual Science, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa 236-0004, Japan.
Background: The prevalence of myopia is increasing dramatically around the world, and many studies have suggested the possibility that ultraviolet (UV) light is effective to prevent the onset and progression of myopia. However, UV is a risk factor for diseases that cause refractive errors such as cataract and pterygium. In this study, we evaluated the relationship between UV exposure and myopia progression.
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