Expressed sequence tags (ESTs) are widely used in gene survey research these years. The EST Pipeline System, software developed by Hangzhou Genomics Institute (HGI), can automatically analyze different scalar EST sequences by suitable methods. All the analysis reports, including those of vector masking, sequence assembly, gene annotation, Gene Ontology classification, and some other analyses, can be browsed and searched as well as downloaded in the Excel format from the web interface, saving research efforts from routine data processing for biological rules embedded in the data.
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http://dx.doi.org/10.1016/s1672-0229(03)01029-5 | DOI Listing |
Diabetes
November 2024
Institut Cochin, CNRS, Inserm, Université Paris Cité, Paris, France.
Murine pancreatic endocrinogenesis has been extensively studied, but human data remain scarce due to limited sample availability. Here, we first built a large collection of human embryonic and fetal pancreases covering the first trimester of pregnancy to explore human endocrinogenesis. Using an experimental pipeline combining in toto staining, tissue clearing, and light-sheet fluorescence microscopy, we show that insulin+, glucagon+, and somatostatin+ cells appear simultaneously at Carnegie Stage (CS) 16.
View Article and Find Full Text PDFSci Rep
November 2024
School of Life Sciences, FHNW University of Applied Sciences and Arts Northwestern Switzerland, Hofackerstrasse 30, Muttenz, 4132, Switzerland.
Early and accurate diagnosis is crucial to prevent disease development and define therapeutic strategies. Due to predominantly unspecific symptoms, diagnosis of autoimmune diseases (AID) is notoriously challenging. Clinical decision support systems (CDSS) are a promising method with the potential to enhance and expedite precise diagnostics by physicians.
View Article and Find Full Text PDFFront Microbiol
September 2024
Animal Health Laboratory, EU/WOAH and National Reference Laboratory for Brucellosis, Anses/Paris-Est University, Maisons-Alfort, France.
Introduction: Mammals are the main hosts for sp., agents of worldwide zoonosis. Marine cetaceans and pinnipeds can be infected by and , respectively.
View Article and Find Full Text PDFPhysiol Meas
June 2024
Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, 2 Worts Causeway, Cambridge, CB2 1TN, UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND.
Neuroimage
July 2024
Département de médecine nucléaire, Groupement Hospitalier Est, Hospices Civils de Lyon, Bron, France; Faculté de Médecine Lyon Est, Université Claude Bernard Lyon 1, Lyon, France; Centre de Recherche en Neurosciences de Lyon, INSERM U1028/CNRS UMR5292, Lyon, France. Electronic address:
Introduction: Spatial normalization is a prerequisite step for the quantitative analysis of SPECT or PET brain images using volume-of-interest (VOI) template or voxel-based analysis. MRI-guided spatial normalization is the gold standard, but the wide use of PET/CT or SPECT/CT in routine clinical practice makes CT-guided spatial normalization a necessary alternative. Ventricular enlargement is observed with aging, and it hampers the spatial normalization of the lateral ventricles and striatal regions, limiting their analysis.
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