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Muscle Strength Decline Caused by Eperisone Hydrochloride: A Case Report.
Clin Ther
January 2024
Department of Pharmacy, School of Pharmacy and Medical Technology, Putian University, Putian, PR China; Key Laboratory of Pharmaceutical Analysis and Laboratory Medicine in University of Fujian Province, Putian University, Putian, PR China. Electronic address:
A 65-year-old female with thoracic spinal stenosis and incomplete paraplegia underwent T11-T12 posterior thoracic interbody fusion. During postoperative rehabilitation, she experienced thigh pain, involuntary lower limb convulsions, and muscle fatigue. Despite being prescribed eperisone hydrochloride for relief, her muscle strength decreased after 14 doses.
View Article and Find Full Text PDFBilateral tonic seizures probably induced by eperisone hydrochloride: a case report.
Front Neurol
September 2023
Department of Neurology, Xiangtan Central Hospital, Xiangtan, Hunan, China.
Eperisone hydrochloride is a central muscle relaxant used to treat osteoporosis. Seizures are rare side effects of eperisone hydrochloride and have been previously reported in the medical literature in overdose situations but not at regular doses. This case report describes a 42-year-old male painter who developed severe bilateral tonic seizures after the initiation of eperisone hydrochloride at regular doses for low back pain.
View Article and Find Full Text PDFTransient depersonalisation/derealisation syndrome from tramadol.
BMJ Case Rep
June 2023
Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Depersonalisation/derealisation (DD) syndrome is often associated with severe traumatic experiences and the use of certain medications. Our patient reported experiencing a transient DD phenomenon a few hours after taking 37.5 mg of tramadol, together with etoricoxib, acetaminophen and eperisone.
View Article and Find Full Text PDFThe associations between central serous chorioretinopathy and muscle relaxants: A case-control study.
Taiwan J Ophthalmol
November 2022
Department of Ophthalmology, NMC Hospital, Al Ain, United Arab Emirates.
Purpose: To evaluate the role of muscle-relaxants as risk factors for the development of central serous chorioretinopathy (CSC) - the second most common retinopathy in our settings; despite multiple risk factors seen in our patients, 21% were initially labelled as idiopathic.
Materials And Methods: Retrospective case-control study at a tertiary hospital in the United Arab Emirates, where we reviewed the medical records of 273 patients with CSC examined between 2010 and 2019 for use of muscle-relaxants including tolperisone/eperisone, carisoprodol and gabapentin/pregabalin within a year of onset/recurrence of the disease. Intake of drugs with known association with CSC (including corticosteroids/sympathomimetics) was also recorded.
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