Higher-order cognition in humans has not generally been viewed as closely entwined with the brain mechanisms mediating more basic perceptual-motor interactions in 3-D space. However, recent findings suggest that perceptual and oculomotor mechanisms that are biased toward the upper field (which disproportionately represents radially distant space) are activated during complex mental operations, ranging from semantic processing to mental arithmetic and memory search. The particularly close affinity with upward conjugate eye deviations--further confirmed in a study of 24 schoolchildren who responded to various mental questions and demands--suggests that active, abstract thinking in humans may have expropriated the focal-extrapersonal brain systems involved in saccadic exploration of the distant environment in other primates.
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| http://dx.doi.org/10.1016/j.actpsy.2004.10.012 | DOI Listing |
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[Establishment and evaluation of a similarity measurement model for orthognathic patients based on the 3D craniofacial features].
Beijing Da Xue Xue Bao Yi Xue Ban
February 2025
Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing 100081, China.
Objective: To establish a similarity measurement model for patients with dentofacial deformity based on 3D craniofacial features and to validate the similarity results with quantifying subjective expert scoring.
Methods: In the study, 52 cases of patients with skeletal Class Ⅲ malocclusions who underwent bimaxillary surgery and preoperative orthodontic treatment at Peking University School and Hospital of Stomatology from January 2020 to December 2022, including 26 males and 26 females, were selected and divided into 2 groups by sex. One patient in each group was randomly selected as a reference sample, and the others were set as test samples.
[Deep learning algorithms for intelligent construction of a three-dimensional maxillofacial symmetry reference plane].
Beijing Da Xue Xue Bao Yi Xue Ban
February 2025
Center for Digital Dentistry, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digi-tal Medical Devices & Beijing Key Laboratory of Digital Stomatology & NHC Research Center of Engineering and Technology for Computerized Dentistry, Beijing 100081, China.
Objective: To develop an original-mirror alignment associated deep learning algorithm for intelligent registration of three-dimensional maxillofacial point cloud data, by utilizing a dynamic graph-based registration network model (maxillofacial dynamic graph registration network, MDGR-Net), and to provide a valuable reference for digital design and analysis in clinical dental applications.
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Automatic Reproduction of Natural Head Position in Orthognathic Surgery Using a Geometric Deep Learning Network.
Diagnostics (Basel)
December 2024
Department of Applied Bioengineering, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 08826, Republic of Korea.
: Accurate determination of the natural head position (NHP) is essential in orthognathic surgery for optimal surgical planning and improved patient outcomes. However, traditional methods encounter reproducibility issues and rely on external devices or patient cooperation, potentially leading to inaccuracies in the surgical plan. : To address these limitations, we developed a geometric deep learning network (NHP-Net) to automatically reproduce NHP from CT scans.
View Article and Find Full Text PDFAngiotensin-Receptor Blockers Prevent Vestibular Schwannoma-Associated Hearing Loss.
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Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Background Introduction: Vestibular schwannoma (VS) tumors typically present with sensorineural hearing loss (SNHL). Losartan has recently demonstrated prevention of tumor-associated SNHL in a mouse model of VS through suppression of inflammatory and pro-fibrotic factors, and the current study investigates this association in humans.
Methods: This is a retrospective study of patients with unilateral VS and hypertension followed with sequential audiometry at a tertiary referral hospital from January 1994 to June 2023.
Head pose-assisted localization of facial landmarks for enhanced fast registration in skull base surgery.
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December 2024
School of Optics and Photonics, Beijing Institute of Technology, Beijing, 100081, Beijing, PR China; Zhengzhou Research Institute, Beijing Institute of Technology, Zhengzhou, 450000, Henan, PR China. Electronic address:
In skull base surgery, the method of using a probe to draw or 3D scanners to acquire intraoperative facial point clouds for spatial registration presents several issues. Manual manipulation results in inefficiency and poor consistency. Traditional registration algorithms based on point clouds are highly dependent on the initial pose.
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