TiCl(4)-promoted multicomponent reactions involving N-tosyl imino ester, cyclic enol ether, and silane reagents in a single one-pot operation provide functionalized alpha-amino acids with multiple stereogenic centers in good to excellent yields. Cis/trans selectivities with optically active substituted dihydrofurans have been investigated.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/ol048302j | DOI Listing |
Publication Analysis
Top Keywords
ticl4-promoted multicomponent
8
functionalized alpha-amino
8
alpha-amino acids
8
multicomponent reaction
4
reaction entry
4
entry functionalized
4
acids ticl4-promoted
4
multicomponent reactions
4
reactions involving
4
involving n-tosyl
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!