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Coexisting sellar Rathke cleft cyst and planum sphenoidale meningioma: illustrative case.
J Neurosurg Case Lessons
January 2025
Department of Neurosurgery, Stanford University School of Medicine, Stanford, California.
Background: The co-occurrence of Rathke cleft cysts (RCCs) and meningiomas in the sellar and parasellar regions represents an exceedingly rare clinical entity. Achieving maximal resection through a single operative approach while minimizing adverse events is challenging, often necessitating multiple surgical approaches, as suggested by previous reports.
Observations: The authors report the case of a 49-year-old female with a history of kidney transplant who presented with headaches and was diagnosed with coexisting RCC and meningioma in the sellar and planum sphenoidale regions, respectively.
Anti-correlation of KLRG1 and PD-1 expression in human tumor CD8 T cells.
Oncotarget
January 2025
Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Recently, combination checkpoint therapy of cancer has been recognized as producing additive as opposed to synergistic benefit due in part to positively correlated effects. The potential for uncorrelated or negatively correlated therapies to produce true synergistic benefits has been noted. Whereas the inhibitory receptors PD-1, CTLA-4, TIM-3, LAG-3, and TIGIT have been collectively characterized as exhaustion receptors, another inhibitory receptor KLRG1 was historically characterized as a senescent receptor and received relatively little attention as a potential checkpoint inhibitor target.
View Article and Find Full Text PDFSupercritical fluid extrusion of pea flour and pea protein concentrate: Effects on off-flavor removal and sensory improvement.
J Food Sci
January 2025
Department of Food Science, Cornell University, Ithaca, New York, USA.
This study was intended to provide a novel process that fills a knowledge gap in relation to the enhancement of pulses utilization. The primary goal was to develop an experimental framework for using a high-pressure supercritical fluid extruder (SCFX) as a continuous bioreactor to produce off-flavor reduced and functionally superior pulse flours and protein concentrates in a single step. The current study focused on using SCFX processing to remove off-flavor from pulse flour and protein concentrates, enhancing the quality, acceptability, and marketability of pulse-based products.
View Article and Find Full Text PDFCausal inference of whole-grain foods' risk based on a generative adversarial network and Bayesian network.
J Food Sci
January 2025
School of Computer and Artificial Intelligence, Beijing Technology and Business University, Beijing, China.
Whole-grain foods (WGFs) constitute a large part of humans' daily diet, making risk identification of WGFs important for health and safety. However, existing research on WGFs has paid more attention to revealing the effects of a single hazardous substance or various hazardous substances on food safety, neglecting the mutual influence between individual hazardous substances and between hazardous substances and basic information. Therefore, this paper proposes a causal inference of WGFs' risk based on a generative adversarial network (GAN) and Bayesian network (BN) to explore the mutual influence between hazardous substances and basic information.
View Article and Find Full Text PDFCompositional Differences of Various Sorption States of Cu and Cd on Goethite in the Presence of Oxyanions: A Quantitative Study.
Langmuir
January 2025
School of Environment and Energy, South China University of Technology, Guangzhou 510006, People's Republic of China.
The anionic species of antimony(V) and phosphate(V) are commonly found in the contaminated soil of mining areas, exerting a significant influence on the sorption of heavy metals and thus affecting their migration. This study quantitatively discussed the sorption mechanism of Sb and P in promoting the sorption of Cd or Cu on goethite through a series of extraction methods. In the single sorption system, the majority of Cu (87-98%) is adsorbed on goethite in the form of EDTA-extractable Cu (EF Cu, possibly inner-sphere complexes) under pH conditions of 3.
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