The MMPIs of 104 cocaine abusers in treatment were subjected to a hierarchical cluster analysis and two basic profile types emerged. Type I consisted of a spike on Pd and a subspike on Hyp, reflecting a rebellious, acting out character-disordered style with narcissistic traits. Type II consisted of a high-ranging, floating profile consisting of marked elevations on F, Sc, Dep, Pt, Pd, and Pa, reflecting a psychiatric patient who concurrently abused cocaine. These findings were contrasted to other MMPI typological studies, and the similarities and differences were discussed.
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http://dx.doi.org/10.3109/00952999208992832 | DOI Listing |
Neuroscience
March 2025
Departamento de Neurofarmacología Experimental, Instituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay. Electronic address:
The number of people suffering from Substance Use Disorder (SUD) worldwide has increased 45 % compared to the last decade according to the latest United Nations World Drug Report. This staggering increase, partly due to the recent COVID-19 pandemic, further raises the social and economic burden for nations. Prevention and treatment, two of the main strategies employed to curb the increase in SUD, have shown limited success despite our increasing understanding of the underlying processes of SUD.
View Article and Find Full Text PDFAm J Public Health
April 2025
All authors are with the Office of the Chief Medical Examiner, San Francisco, CA. Luke N. Rodda is also with the Department of Laboratory Medicine, University of California, San Francisco.
To identify drug prevalence through the analysis of drug material and paraphernalia (DMP) collected from scenes of fentanyl-involved fatal accidental drug overdoses in San Francisco, California, throughout 2022. We conducted gas chromatography-mass spectrometry testing on 409 items of DMP (e.g.
View Article and Find Full Text PDFAddict Biol
March 2025
Departament de Psicologia Bàsica, Clínica i Psicobiologia, Universitat Jaume I, Castellón, Spain.
Repetitive drug use results in enduring structural and functional changes in the brain. Addiction research has consistently revealed significant modifications in key brain networks related to reward, habit, salience, executive function, memory and self-regulation. Techniques like Voxel-based Morphometry have highlighted large-scale structural differences in grey matter across distinct groups.
View Article and Find Full Text PDFBackground: Illicit opioids, including fentanyl, are linked to unprecedented levels of overdose in Canada and elsewhere. The risks associated with illicit opioids can include high potency, unpredictable concentration and the unexpected presence in other drugs. Within this context, we examine drug checking data to better understand the presence of illicit opioids such as fentanyl in other drugs and possible ways to interpret these results.
View Article and Find Full Text PDFFront Oral Health
February 2025
Department of Conservative Dentistry and Periodontology, University Hospital Regensburg, Regensburg, Germany.
Objectives: Opioid use has significantly increased in Germany in recent years. This study aimed to evaluate and compare the oral health, dental hygiene, self-perceived pain, and functional limitations of opioid-addicted patients with a healthy control group.
Materials And Methods: 50 opioid-addicted patients (OAP) attending substitution treatment at the Centre for Addiction Medicine of the Department of Psychiatry and Psychotherapy at the University of Regensburg were enrolled and interviewed about their drug use history.
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