Objective: The authors had for aim to determine the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) strains on infections in Abidjan as well as their susceptibility to other antibiotics.
Methods: Three hundred and forty strains of S. aureus from various samples of hospitalized patients were studied. Methicillin-resistance was assessed using oxacillin disk diffusion in agar. The MRSA, once detected, were confirmed by screening in Mueller-Hinton agar containing oxacillin at 6 microg/ml. The susceptibility to other antibiotics was analyzed using an antibiogram in agar medium.
Results: Twenty-five percent of strains were resistant to methicillin (MRSA strains). Those MRSA were identified mainly in blood culture (14.2%), pus (4%) and urine (1.9%). Samples were collected in neonatal unit (13%), surgical units (5.4%) and intensive care unit (3.4%). A variable proportion of MRSA expressed resistance to other families of antibiotics: aminoglycosides 77.6%, rifampicin 8.8%, fluoroquinolones 34.1% and vancomycin 5.9%.
Conclusion: Circulation of multidrug resistant MRSA in hospital, especially in neonatal unit, should lead to surveillance. Risk factors and other associated markers need to be identified.
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http://dx.doi.org/10.1016/j.medmal.2003.12.001 | DOI Listing |
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