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The American Society for Microbiology sponsored the 38th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), a premier annual scientific conference, in San Diego, California, September 24-27, 1998. At the ICAAC several sessions were held which focused on the pathogenesis of fungal disease, the in vitro susceptibility testing of new azole (voriconazole, Syn-2869, SCH-56592, carbendazim), echinocandin-like (FK-463, LY-303366, MK-0991), polyene (patricins) and established antifungal agents (fluconazole, itraconazole, amphotericin B, nystatin, terbinafine), the experimental in vivo activity of these new antifungal drugs in various animal models of fungal disease, and the clinical activity of fluconazole, itraconazole and liposomal amphotericin B formulations.
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Plant Dis
March 2025
University of Bologna, Department of Agricultural and Food Sciences (DISTAL), Bologna, Bologna, Italy;
species from the Acutatum complex are well-known pathogens responsible for Apple Bitter Rot in post-harvest apples across Europe, including Italy. In recent years, however, Apple Bitter Rot has become a significant pre-harvest issue, affecting both fruit and leaves. This is concerning, as species also cause Glomerella Leaf Spot, a damaging foliar disease.
View Article and Find Full Text PDFPlant Dis
March 2025
University of Minnesota, Plant Pathology, 1991 Upper Buford Cir., 495 Borlaug Hall, St. Paul, Minnesota, United States, 55108;
Wild grasses can serve as hosts for plant pathogens that attack small grain cereal crops, thereby perpetuating the disease cycle and potentially initiating epidemics. Foxtail barley () is a perennial grass species that is common across North America and can often be found growing near cultivated barley fields. Despite the close proximity of the two plant species in agro-ecosystems, few studies have been advanced to characterize the compatibility of to barley pathogens and its possible role in disease epidemiology.
View Article and Find Full Text PDFSci Rep
March 2025
MSc Program in Molecular Biology and Genetics, School of Graduate Studies, Çanakkale Onsekiz Mart University, Çanakkale, Türkiye.
The mycobiome is comprised of a rich array of fungal species that compete for resources, and species diversity and prevalence exhibit a dynamic structure under the influence of many factors. While the host fruit develops, the prevalence and the arrangement of fungal species in this mycobiome also change, forming a dynamic microenvironment. In this study, fungal diversity on peach fruit surfaces at different developmental stages have been determined to better understand the changes in fungal diversity and disease occurrence by using metabarcoding of the full ITS region and processing the obtained high-throughput sequencing data with various bioinformatic analyses.
View Article and Find Full Text PDFJ Infect
March 2025
UK Health Security Agency, Field Services North West, Liverpool, L1 3DS. Electronic address:
Objectives: Revised UK guidelines for the management of contacts of invasive group A Streptococcus (iGAS) infection in community settings were published in December 2022. We present the findings of a narrative review which informed the public health recommendations around the provision of antibiotic chemoprophylaxis detailed in the updated guidelines.
Methods: We conducted a literature review of studies reporting the risk of iGAS infection associated with specific risk factors.
Exp Eye Res
March 2025
Department of Ophthalmology, The Affiliated Hospital of Qingdao University, No. 16 Jiangsu Road, Qingdao, Shandong Province, 266003, China. Electronic address:
Fungal keratitis is a vision-threatening corneal infectious disease. However, clinically therapeutic medicines cannot attain ideal efficacy due to limited control of fungal virulence and excessive inflammatory response. Carnosic acid (CA) is a phenolic diterpene, which has been reported to have multiple abilities including antibacterial, anti-inflammatory and antioxidant.
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