Incubation in CO(2) resulted in higher (> or =3 doubling dilution) MICs of telithromycin than those found in ambient air for 31.2% of 346 Streptococcus pneumoniae ermB-positive strains. An increased telithromycin MIC in CO(2) was not correlated with loss of its activity in the murine sepsis/peritonitis model.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC538872 | PMC |
| http://dx.doi.org/10.1128/AAC.49.1.464-466.2005 | DOI Listing |
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