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Aims: Whether prior treatment with angiotensin-converting enzyme inhibitors (ACEi) or angiotensin receptor blockers (ARBs) modifies efficacy and safety of sacubitril/valsartan (Sac/Val) in patients with heart failure (HF) and ejection fraction (EF) >40% is unclear, thus Sac/Val according to ACEi/ARB status at baseline was assessed.
Methods And Results: This was a pre-specified analysis of Prospective comparison of ARNI with ARB Given following stabiLization In DEcompensated HFpEF (PARAGLIDE-HF), a double-blind, randomized controlled trial of Sac/Val versus valsartan, categorizing patients according to baseline ACEi/ARB status. The primary endpoint was time-averaged proportional change in N-terminal pro-B-type natriuretic peptide (NT-proBNP) from baseline through weeks 4 and 8.
Video atlas of pulmonary segmentectomy: robotic-assisted right S3 segmentectomy with 3-dimensional imaging.
Multimed Man Cardiothorac Surg
January 2025
New Cross Hospital, Royal Wolverhampton NHS Trust, Wolverhampton, United Kingdom.
Robotic-assisted thoracic surgery has become increasingly utilized in recent years. Complex lung cancer resection surgery can be performed using a robotic approach. It facilitates 3-dimentional visualization of structures, enhanced manipulation of tissues and precise movements.
View Article and Find Full Text PDFEffectiveness of Braille and ATP Technique in Improving Oral Hygiene Status of Visually Impaired Children: An Interventional Study.
J Contemp Dent Pract
September 2024
Department of Public Health Dentistry, MES Dental College and Hospital, Malappuram, Kerala, India.
Aim: The study aimed to subject two groups of visually challenged children to Braille and audio-tactile performance (ATP) techniques of oral health education and compare the effectiveness of each technique through a comparison of OHI-S index scores.
Materials And Methods: 30 visually challenged children of 6-12 years belonging to a Government-aided blind school were divided into two study groups based on the method of oral health education ( = 15). Group I received oral hygiene instructions in Braille while group II received instructions through audio clips, tactile sensations of tooth models, and closely supervised performance of brushing technique.
Trigger Point Dry Needling to Reduce Pain and Improve Function and Postural Control in People With Ankle Sprain: A Systematic Review and Meta-Analysis.
J Chiropr Med
September 2024
Department of Health, Nutrition and Exercise Sciences, North Dakota State University, Fargo, North Dakota.
Objective: The purpose of this review was to evaluate the effectiveness of dry needling (DN) to improve function, proprioception, and balance and to reduce pain in individuals with chronic ankle instability (CAI).
Methods: We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines for this review. We searched PubMed, ISI Web of Knowledge, Scopus, Science Direct, Google Scholar, and ProQuest databases from inception until July 2022 using the PICO (population, intervention, comparison, outcome) method.
Linkage and association analysis to identify wheat pre-harvest sprouting resistance genetic regions and develop KASP markers.
Mol Breed
January 2025
College of Agronomy, Northwest A&F University, Yangling, 712100 Shaanxi China.
Unlabelled: Pre-harvest sprouting (PHS) of wheat ( L.) is one of the complex traits that result in rainfall-dependent reductions in grain production and quality worldwide. Breeding new varieties and germplasm with PHS resistance is of great importance to reduce this problem.
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