Objective: Present a revised neurosurgical technique for insertion of the Ommaya reservoir that we have routinely utilized and found to have fewer complications that the standard approach.
Experimental Design: Randomized retrospective study of 20 patients who underwent insertion of Ommaya reservoir with the preassembled technique.
Setting: Major university hospital.
Patients Or Participants: Twenty patients who underwent Ommaya reservoir placement within the last 5 years were randomly selected for chart and computed tomography review.
Interventions: A new preassembled technique for Ommaya reservoir placement was utilized in all 20 patients.
Measures: Retrospective review of the patient records and computed tomography scans of 20 patients undergoing Ommaya placement were performed to assess ventricular catheter placement and any postoperative complications.
Results: In all 20 patients, we had consistent ipsilateral right frontal horn placement of ventricular catheter and had no postoperative morbidities, reoperations for ventricular catheter positioning or mortalities.
Conclusions: This technique reduces overall operative time, decreases risk for intraoperative infection, and poor ventricular catheter placement by eliminating the manipulation step of connecting the reservoir to the catheter in vivo.
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http://dx.doi.org/10.1002/jso.20174 | DOI Listing |
Clin Cancer Res
December 2024
Mayo Clinic, Rochester, United States.
Purpose: Current methods for glioma response assessment are limited. This study aimed to assess the technical and clinical feasibility of molecular profiling using longitudinal intracranial CSF from patients with gliomas.
Experimental Design: Adults with gliomas underwent longitudinal intracranial CSF collection via Ommaya reservoirs or ventriculoperitoneal shunts.
BMC Immunol
December 2024
Department of Neurosurgery/Neuro-Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, People's Republic of China.
Purpose: Immunotherapy is a promising treatment for cancers but should be optimized for malignant gliomas. Because of immune privilege feature of the brain, local administration of immunotherapy may be a promising strategy for malignant glioma treatment. Identification of patients who may benefit from local immunotherapy is essential.
View Article and Find Full Text PDFCureus
November 2024
Neurosurgery, King Hamad University Hospital, Busaiteen, BHR.
This report presents the case of a seven-year-old child diagnosed with Grisel's syndrome following a craniotomy for a cystic brain lesion. The patient initially presented with persistent, progressively worsening headaches that coincided with neurological symptoms. Imaging revealed a massive cystic lesion causing a significant compression and midline shift.
View Article and Find Full Text PDFFront Immunol
December 2024
Department of Neurology Medicine, The Second Hospital of Shandong University, Cheeloo College of Medicine of Shandong University, Shandong University, Jinan, China.
We report on a previously non-HIV-diagnosed, 47-year-old male diagnosed with diabetes mellitus (DM) and cryptococcal meningoencephalitis, who was referred to our institution for antifungal treatment. During the course of treatment, due to the development of refractory intracranial hypertension, Ommaya reservoirs were employed for cranial pressure reduction. The patient gradually recovered during subsequent antifungal therapy; however, symptoms worsened in the third month of treatment, leading to consideration of post-infectious inflammatory response syndrome (PIIRS) on examination.
View Article and Find Full Text PDFWorld Neurosurg
December 2024
Department of Neurosurgery, Affiliated Cancer Hospital of Shandong First Medical University, China. Electronic address:
Objectives: To evaluate the efficacy and prognosis of intraventricular medication administered via the reservoir of Ommaya or ventricular shunt system to control leptomeningeal metastases, with or without ventricular shunt based on intracranial pressure, in combination with postoperative systemic therapy.
Methods: Between April 2021 and December 2022, 125 patients with leptomeningeal metastases were managed in our department who underwent Ommaya reservoir placement and/or ventricular shunt and subsequently received intraventricular medication postoperatively. The extent of symptom amelioration and survival, as well as the determinants influencing prognosis, were evaluated.
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