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http://dx.doi.org/10.1093/genetics/168.4.1773 | DOI Listing |
Nanoscale
January 2023
Department of Physics, King's College London, The Strand, London, WC2R 2LS, UK.
Fluorescent InP-based quantum dots have emerged as valuable nanomaterials for display technologies, biological imaging, and optoelectronic applications. The inclusion of zinc can enhance both their emissive and structural properties and reduce interfacial defects with ZnS or CdS shells. However, the sub-particle distribution of zinc and the role this element plays often remains unclear, and it has previously proved challenging to synthesise Zn-alloyed InP-based nanoparticles using aminophosphine precursors.
View Article and Find Full Text PDFVoriconazole-associated periostitis (VAP) is an underrecognized and unpredictable side effect of long-term voriconazole therapy. We report two cases of VAP occurring in the post-transplant setting: a 68-year-old lung transplant recipient who required ongoing voriconazole therapy, in whom urinary alkalinization was used to promote fluoride excretion and minimize voriconazole-related skeletal toxicity, and a 68-year-old stem-cell transplant recipient with a high voriconazole dose requirement, identified on pharmacogenomic testing to be a CYP2C19 ultrarapid metabolizer, the dominant enzyme in voriconazole metabolism. This is the first reported case of pharmacogenomic profiling in VAP and may explain the variability in individual susceptibility to this uncommon adverse effect.
View Article and Find Full Text PDFNature
December 2020
Centre for Biodiversity and Conservation Science, School of Earth and Environmental Sciences, University of Queensland, St Lucia, Queensland, Australia.
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
View Article and Find Full Text PDFNature
October 2020
Centre for Biodiversity and Conservation Science, School of Earth and Environmental Sciences, University of Queensland, St Lucia, Queensland, Australia.
Humanity will soon define a new era for nature-one that seeks to transform decades of underwhelming responses to the global biodiversity crisis. Area-based conservation efforts, which include both protected areas and other effective area-based conservation measures, are likely to extend and diversify. However, persistent shortfalls in ecological representation and management effectiveness diminish the potential role of area-based conservation in stemming biodiversity loss.
View Article and Find Full Text PDFThe world's protected area network is constantly changing, and the dynamics of this network are tracked using the World Database on Protected Areas (WDPA). This database evolved from a list of protected areas first mandated by the United Nations in 1959, and it now informs the key indicators that track progress toward area-based conservation targets. In this capacity, the WDPA illuminates the role of protected areas in advancing a range of international objectives and agreements, including the Convention on Biological Diversity and the Sustainable Development Goals.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!