A dedicated cell-based biological test system was used for studying specific effects of myostatin and other human growth factors on the proliferation of cultured myoblasts and fibroblasts. Myostatin inhibited myoblast growth without affecting human fibroblasts. In this test system, human growth hormone and insulin-like growth factor I acted as antagonists of myostatin, which indicates that these agents have a potential for blocking its effects in vivo.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
growth factors
8
test system
8
human growth
8
growth
5
[effects myostatin
4
myostatin growth
4
factors cultured
4
human
4
cultured human
4
human cells]
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!