Accommodative lags, induced by a target at 33 cm (distance-induced condition) and by a -3.0 D lens (lens-induced condition), and wavefront aberrations were measured in 27 young myopic eyes. The accommodative lags and Strehl ratios derived from the wavefront aberrations in myopes were compared with those from 57 emmetropes. Accommodation was measured using a Canon R-1 autorefractor, while aberrations were measured using a psychophysical ray-tracing technique. In accord with previous results, larger accommodative lags were found for the myopes than the emmetropes in both the lens-induced and distance-induced conditions. The mean Strehl ratio was smaller in the myopes (0.079) than the emmetropes (0.091); this difference approached significance (p = 0.055). In addition, for myopes the accommodative lag was significantly correlated with the Strehl ratio in the lens-induced condition (r = -0.45, p < 0.02) and approached significance in the distance-induced condition (r = -0.35, p = 0.07). No significant correlations were found for emmetropes. Possible reasons to account for these results are discussed.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.visres.2004.08.027 | DOI Listing |
Ophthalmic Physiol Opt
January 2025
School of Optometry, Indiana University, Bloomington, Indiana, USA.
Purpose: To evaluate the myopic and hyperopic defocus delivered to the retina by a dual focus (DF) myopia control contact lens when myopia exceeds 6.00 D.
Methods: Individuals with high myopia were fitted bilaterally with high-powered DF lenses containing power profiles matching a Coopervision MiSight 1 day contact lens (omafilcon A) and a Coopervision Proclear 1 day single vision (SV) lens.
In Silico Pharmacol
April 2024
University of Lille, Inserm, U1286, INFINITE, Lille Inflammation Research International Center, Institut de Chimie Pharmaceutique Albert Lespagnol (ICPAL)Faculté de Pharmacie, 3 rue du Professeur Laguesse, 59,000 Lille, France.
Unlabelled: Tetraspanin CD81 is a transmembrane protein used as a co-receptor by different viruses and implicated in some cancer and inflammatory diseases. The design of therapeutic small molecules targeting CD81 lags behind monoclonal antibodies and peptides but different synthetic and natural products binding to CD81 have been identified. We have investigated the interaction between synthetic compounds and CD81, considering both the cholesterol-bound full-length receptor and a truncated protein corresponding to the large extracellular loop (LEL) of the tetraspanin.
View Article and Find Full Text PDFOphthalmic Physiol Opt
January 2024
Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Purpose: Previous transverse and a handful of longitudinal studies have shown that the slope of the static accommodation response/stimulus curve declines as complete presbyopia is approached. Changes in pupillary miosis and ocular spherical aberration (SA) are also evident. This study further investigated longitudinal changes in the relationships between the monocular static accommodative response, pupil diameter and SA of a single adult.
View Article and Find Full Text PDFInvest Ophthalmol Vis Sci
November 2023
Indiana University School of Optometry, Bloomington, Indiana, United States.
Purpose: Uncorrected hyperopic children must overcome an apparent conflict between accommodation and vergence demands to focus and align their retinal images. This study tested hypotheses about simultaneous accommodation and vergence performance of young hyperopes to gain insight into ocular motor strategies used to maintain eye alignment.
Methods: Simultaneous eccentric photorefraction and Purkinje image tracking were used to assess accommodative and vergence responses of 26 adult emmetropes (AE) and 94 children (0-13 years) viewing cartoons.
World Neurosurg
November 2023
Section of Neurosurgery, Department of Surgery, Aga Khan University, Karachi, Pakistan. Electronic address:
Background And Objective: According to the World Federation of Neurosurgical Societies (WFNS), a minimum neurosurgery workforce density should be 1 per 200,000 population for optimum access to neurosurgical care. Pakistan lags behind in the number of neurosurgeons, and disproportionate geographical distribution further increases disparity. Our objective was to geographically map the density of neurosurgeons and emergency neurosurgical services (ENS) in Pakistan.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!