Asymmetric synthesis of the AB ring system of lactonamycin.

Org Lett

E. F. Merkert Chemistry Center, Boston College, Chestnut Hill, Massachusetts 02467, USA.

Published: December 2004

[reaction: see text] An enantiospecific synthesis of the AB fragment of lactonamycin (5) is achieved in eight steps from dimethyl D-tartrate. Ester enolate chemistry features prominently in the sequence.

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Source
http://dx.doi.org/10.1021/ol047922hDOI Listing

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