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Correlation Between Grade of Clinical Response to Neoadjuvant Therapy for Rectal Cancer and Oncologic Outcomes in the Era of Watch-and-Wait.
Dis Colon Rectum
November 2024
Department of Colon and Rectal Surgery, Memorial Sloan Kettering Cancer Center, New York.
Background: The watch-and-wait strategy provides an opportunity to pursue non-operative management in rectal cancer patients with clinical complete response after neoadjuvant therapy. The management of those with near complete response remains controversial.
Objective: We assessed the oncologic outcomes of patients managed by watch-and-wait versus total mesorectal excision according to clinical response to neoadjuvant therapy.
Clinically Significant and Germline Variants in Breast Cancer-A Single-Center Experience.
Cancers (Basel)
December 2024
Regional Centre of Medical Genetics Dolj, Emergency County Hospital Craiova, 200642 Craiova, Romania.
Background: Conditions associated with pathogenic (PVs) or likely pathogenic variants (LPVs) are often severe. The early detection of carrier status is ideal, as it provides options for effective case management.
Materials And Methods: The study involved 58 patients with a personal and familial history of breast cancer (BC) who underwent genetic testing at the Regional Centre for Medical Genetics Dolj over a three-year period.
Approaching Universal Prenatal Detection of Significant Cardiovascular Malformations in Nevada.
Prenat Diagn
December 2024
Children's Heart Center Nevada, Las Vegas, Nevada, USA.
Objective: To report our recent experience with prenatal detection of significant cardiovascular malformations (CVMs) in Nevada's state-wide maternal population receiving prenatal care.
Methods: We queried our databases for those with significant CVMs diagnosed pre- or postnatally between May 1, 2021, and April 30, 2024. We defined CVMs as those that required, would have required, or will likely require a therapeutic procedure in the first 12 months.
Three Years of Stable Water Isotope Data of Daily Rain Samples Collected from Three Geomorphic Regions of India.
Sci Data
December 2024
Centre for Climate Change Research, Indian Institute of Tropical Meteorology, Ministry of Earth Sciences, Pune, India.
High-frequency precipitation (solid/liquid) isotope datasets are useful for identification of moisture sources and various dynamical and thermodynamical processes controlling precipitation formation. Here, we report three-year (2019-2021) daily rain isotope (both oxygen, δO hereafter, and hydrogen, δH, hereafter) datasets from three unique locations in India during the Indian Summer Monsoon (ISM). The locations are- (1) Port Blair- an island situated in the Bay of Bengal (BoB); (2) Mahabaleshwar, located at the crest of the Western Ghats Mountain; and (3) Tezpur, in northeast India, situated close to a dense forest.
View Article and Find Full Text PDFThree-Year Assault Cases Performed on the Emergency Trauma Center.
Medeni Med J
December 2024
İstanbul Training and Research Hospital, Clinic of Neurosurgery, İstanbul, Türkiye.
Objective: This study aims to compare the results of cases with a history of assault presented to our emergency department over a period of three years with literature data and to share our experiences with colleagues.
Methods: Demographic characteristics, trauma findings, clinical conditions, surgical interventions, mortality, and outcomes of patients with a history of assault to the emergency department between 2020 and 2022 were retrospectively examined. The results were analyzed using the Number Cruncher Statistical System 2007 Statistical Software package program (Utah, USA).
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