Caffeine: a valuable tool to study central fatigue in humans?

Exerc Sport Sci Rev

Department of Biology and 2School of Kinesiology and Health Science, York University, Toronto, Ontario, Canada.

Published: October 2004

This review focuses on caffeine's effects on the central modulation of muscle activation in humans. The drug's effects on voluntary muscle activation, the Hoffman reflex, motor-evoked potentials, self-sustained firing, pain, and sensation are discussed, and the possibility that caffeine maybe useful in the study of central fatigue is explored.

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Source
http://dx.doi.org/10.1097/00003677-200410000-00004DOI Listing

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