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Rhodococcus pyridinovorans MW3, a bacterium producing a nitrile hydratase. | LitMetric
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Rhodococcus pyridinovorans MW3, a bacterium producing a nitrile hydratase.

Sylvain Precigou Marco Wieser Patrick Pommares Philippe Goulas Robert Duran

Biotechnol Lett

Laboratoire d'Ecologie Moléculaire, IBEAS, EA 3525, Université de Pau et des Pays de l'Adour, avenue de l'Université, UFR Sciences et Techniques, BP 1155 F-64013, Pau cedex, France.

Published: September 2004

Rhodococcus pyridinovorans MW3 was isolated from an arable land of manioc from the Congo for its ability to transform acrylonitrile to acrylamide. This strain contains a cobalt nitrile hydratase (NHase) showing high sequence homology with NHases so far described. The specific NHase activity was 97 U mg(-1) dry wt. NHase production by R. pyridinovorans MW3 was urea and Co-dependent. The NHase was active for acrylamide up to 60% (w/v) indicating its potential for acrylamide production.

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http://dx.doi.org/10.1023/B:BILE.0000045636.47527.99DOI Listing

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