AI Article Synopsis
- The study explores new control strategies for ticks by using high throughput genomics to identify relevant genes related to reproduction, defense, and feeding.
- Researchers analyzed the transcriptomes of various tick tissues, generating over 1,344 expressed sequence tags (EST) with about 30% representing novel sequences.
- This research aims to contribute to the NCBI database and provides a foundation for developing immunobiological or chemical control methods against ticks.
Article Abstract
The quest for new control strategies for ticks can profit from high throughput genomics. In order to identify genes that are involved in oogenesis and development, in defense, and in hematophagy, the transcriptomes of ovaries, hemocytes, and salivary glands from rapidly ingurgitating females, and of salivary glands from males of Boophilus microplus were PCR amplified, and the expressed sequence tags (EST) of random clones were mass sequenced. So far, more than 1,344 EST have been generated for these tissues, with approximately 30% novelty, depending on the the tissue studied. To date approximately 760 nucleotide sequences from B. microplus are deposited in the NCBI database. Mass sequencing of partial cDNAs of parasite genes can build up this scant database and rapidly generate a large quantity of useful information about potential targets for immunobiological or chemical control.
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| http://dx.doi.org/10.1196/annals.1307.037 | DOI Listing |
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