Synthesis and antiviral activity against Coxsackie virus B3 of some novel benzimidazole derivatives.

Bioorg Med Chem Lett

School of Chemistry and Chemical Engineering, Shanghai Jiaotong University, Shanghai 200240, PR China.

Published: January 2005

Some benzimidazole derivatives were synthesized and evaluated for their antiviral properties. Compounds 20 and 21 showed potent selective activity against Coxsackie virus B(3) in VERO cells. Some structure-activity relationships were discussed.

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http://dx.doi.org/10.1016/j.bmcl.2004.10.087DOI Listing

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