The autoradiographic micromapping of rocks with various U and Th contents has been performed by means of CR-39 solid-state nuclear track detector (SSNTD). The optical track density was found to be highly correlated (r=0.92) with total alpha emitters activity calculated on the basis of field gamma spectrometric measurements of rock outcrops. The method was tested not only for the wide range activities of alpha emitters but various types of surface distribution (including highly radioactive mineral grains) as well.
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http://dx.doi.org/10.1016/j.jenvrad.2004.05.017 | DOI Listing |
Med Phys
January 2025
Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Background: Diffusing alpha-emitters Radiation Therapy ("Alpha DaRT") is a promising new radiation therapy modality for treating bulky tumors. Ra-carrying sources are inserted intratumorally, producing a therapeutic alpha-dose region with a total size of a few millimeter via the diffusive motion of Ra's alpha-emitting daughters. Clinical studies of Alpha DaRT have reported 100% positive response (30%-100% shrinkage within several weeks), with post-insertion swelling in close to half of the cases.
View Article and Find Full Text PDFNucl Med Biol
January 2025
Nuclear Physics Institute of the Czech Academy of Sciences, Řež, Czech Republic.
Limited availability constrains the implementation of Ac, the most promising α emitter for targeted therapy, in clinical practice. Proton activation of Ra is one of few realistic solutions to this problem. We have therefore measured cross sections of relevant Ra(p,xn) nuclear reactions in the energy range of 12.
View Article and Find Full Text PDFEJNMMI Radiopharm Chem
January 2025
Department of Nuclear Medicine and Medical Physics, Karolinska University Hospital, Stockholm, 171 76, Sweden.
Background: Beyond the use of conventional short-lived PET radionuclides, there is a growing interest in tracking larger biomolecules and exploring radiotheranostic applications. One promising option for imaging medium-sized molecules and peptides is ⁵⁵Co (T₁/₂ = 17.5 h, β⁺ = 76%), which enables imaging of new and already established tracers with blood circulation of several hours.
View Article and Find Full Text PDFNucl Med Biol
December 2024
Life Sciences Division, TRIUMF, BC V6T 2A3 Vancouver, British Columbia, Canada; Department of Chemistry, University of British Columbia, V6T 1Z1 Vancouver, British Columbia, Canada.
Targeted Alpha Therapy has shown great promise in cancer treatment, sparking significant interest over recent decades. However, its broad adoption has been impeded by the scarcity of alpha-emitters and the complexities related to their use. The availability of these radionuclides is often constrained by the intricate production processes and purification, as well as regulatory and logistical challenges.
View Article and Find Full Text PDFNano Lett
January 2025
Department of Physics and Astronomy, Seoul National University, 08826 Seoul, Korea.
Quantum emitters in solid-state materials are highly promising building blocks for quantum information processing and communication science. Recently, single-photon emission from van der Waals materials has been reported in transition metal dichalcogenides and hexagonal boron nitride, exhibiting the potential to realize photonic quantum technologies in two-dimensional materials. Here, we report the generation of room temperature single-photon emission from exfoliated and thermally annealed single crystals of van der Waals α-MoO.
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