Worldwide, malaria is the most prevalent vector-borne disease, endemic or hyperendemic in more than 100 countries. The disease is transmitted to humans by the bite of an infected female Anopheles mosquito, a protozoan of the genus Plasmodium with a life cycle split between man (the vertebrate host) and the mosquito vector. Since the 1960s, Israel has been considered a malaria free country, despite a substantial number of imported cases each year (mainly P. falciparum originating in Africa and P. vivax). Between 60-100 imported malaria cases are registered annually due to young people traveling to endemic countries and immigration from sub-Saharan Africa. However, since successful malaria control was achieved without the elimination of local Anopheles populations, concern about the possibility of renewed malaria transmission in Israel is increasing. Among travelers to malaria endemic countries, the disease can usually be prevented with prophylactic use of antimalarial drugs and strict measures to prevent mosquito bites. If, on their return, travelers become ill, they should seek prompt medical attention and inform their physician which countries they have visited. For their part, physicians should not fail to elicit travel history as part of the routine fever workup. Finally, intensive surveillance and control of the mosquito populations is also imperative to diminish the risk of reestablishment of malaria transmission.
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West Afr J Med
September 2024
Department of Paediatrics, Federal Teaching Hospital, Ido-Ekiti. Email: Tel: +2348035741951.
Background: The vital statistics in the third world countries are poor and have witnessed minimal improvement over the years with childhood mortality in Nigeria remaining one of the highest among the developing countries despite various child survival programmes. Child survival strategies can only be efficient if the major reasons for morbidity are known. The objective of this retrospective study was to review the patterns of childhood mortality at the emergency room of the Federal Teaching Hospital, Ido-Ekiti (FETHI).
View Article and Find Full Text PDFBMC Neurol
January 2025
Department of Radiology, School of Medicine, College of Medicine and Health Sciences, Mizan-Tepi University, Mizan-Teferi, Ethiopia.
Background: Malaria is an infectious disease caused by Plasmodium parasites, transmitted to humans by infected female Anopheles mosquitoes. Five Plasmodium species infect humans: P. vivax, P.
View Article and Find Full Text PDFMalar J
January 2025
PATH, 2201 Westlake Ave Ste 200, Seattle, WA, 98121, USA.
Background: The World Health Organization conditionally recommends reactive drug administration to reduce malaria transmission in settings approaching elimination. However, few studies have evaluated the impact of reactive focal drug administration (rFDA) in sub-Saharan Africa, and none have evaluated it under programmatic conditions. In 2016, Senegal's national malaria control programme introduced rFDA, the presumptive treatment of compound members of a person with confirmed malaria, and reactive mass focal drug administration (rMFDA), an expanded effort including neighbouring compounds during an outbreak, in 10 low transmission districts in the north of the country.
View Article and Find Full Text PDFMalar J
January 2025
Department of Parasitology-Mycology and Tropical Medicine, Université Des Sciences de La Santé de Libreville, BP 4009, Libreville, Gabon.
Background: The negative impact of COVID-19 pandemic on healthcare service utilization has been reported in several countries. In Gabon, data on the preparedness for future pandemic are lacking. The aim of the present study was to assess the trends of hospital attendance, malaria and self-medication prevalences as well as ITN use before and during Covid-19 first epidemic waves in a paediatric wards of a sentinel site for malaria surveillance, in Libreville, Gabon.
View Article and Find Full Text PDFTrends Parasitol
January 2025
Department of Molecular Parasitology, Institute of Biology, Humboldt Universität zu Berlin, 10115 Berlin, Germany. Electronic address:
Metabolically active, genetically attenuated Plasmodium falciparum parasite lines are promising second-generation malaria vaccine candidates. Lamers et al. and Roozen et al.
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