Bowenoid papulosis is a pre-malignant condition affecting the ano-genital area. Pathogenesis may be associated with high-risk human papillomavirus genotypes, and sexual transmission is the most likely mode of acquisition. Risk of progression to invasive disease is low. Treatment usually involves locally destructive or ablative therapies. We report well-tolerated, successful clearance of bowenoid papulosis of the penis in a 25-year-old male, using topical Aldara (imiquimod) cream 5%, once every other day for two months.
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Article Synopsis
- The article presents a clinical case of a young patient with HPV-associated penile intraepithelial neoplasia (PIN), specifically the erythematous form of bowenoid papulosis.
- It highlights the issues of delayed diagnosis due to improper diagnostic approaches and a lack of awareness among doctors about cancer-related diseases.
- The piece emphasizes the significance of early detection in preventing progression to more severe conditions like squamous cell penile carcinoma, detailing the different subtypes of PIN and their varying risks of leading to cancer.
The combination of holmium laser and ALA-PDT for Bowenoid Papulosis with diffuse large B-cell lymphoma.
Photodiagnosis Photodyn Ther
February 2024
Institute of Photomedicine, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai 200443, China. Electronic address:
Article Synopsis
- Bowenoid Papulosis (BP) is a pre-cancerous condition that affects the anogenital area and can become serious if combined with immunosuppression, leading to potential complications like squamous cell carcinoma.
- A complex case involving BP, Bowen's disease, and Diffuse Large B-Cell Lymphoma was treated successfully using a combination of holmium laser therapy and 5-Aminolevulinic Acid Photodynamic Therapy (ALA-PDT).
- After treatment, the lesion completely disappeared and there was no recurrence of the affected area for five years.
Clinical and histopathological characteristics, diagnosis and treatment, and comorbidities of Bowen's disease: a retrospective study.
Front Med (Lausanne)
November 2023
Department of Dermatology, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China.
Article Synopsis
- Bowen's disease (BD) is a precancerous skin condition that often gets misdiagnosed due to similarity with other skin diseases, with a study showing a diagnosis accuracy of just 54%.
- A retrospective study of 50 patients revealed that the average onset age was 55.1 for males and 58.2 for females, with the disease duration averaging 25.3 months for males and 33.9 months for females, but there were no significant differences based on gender.
- The study also found that 66% of BD patients had other health conditions, with skin diseases being the most common comorbidity, while the majority of cases showed signs of squamous-cell hyperplasia and other atypical cellular characteristics
Dermoscopy of condyloma lata: An observational controlled study.
Australas J Dermatol
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Private practice, Vicenza, Trento, Italy.
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