Rabbits (Oryctolagus cuniculus) were presented with 7 daily sessions of tone-alone training after conditioning. Before the beginning of each of the first 4 extinction sessions, an artificial tear solution or tetracaine hydrochloride was administered to the cornea of rabbits in the control group (n = 6) and experimental group (n = 7), respectively. There were no between-group differences in the percentage of conditioned responses between both groups. However, the amplitude of the conditioned response was notably reduced in the tetracaine group (M = 0.40, SEM +/- 0.216) relative to the control group (M = 1.32, SEM +/- 0.639) early in extinction. Results seem to suggest that although motor output has been found to play an important role in extinction, corneal sensory feedback is not necessary.
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http://dx.doi.org/10.1037/0735-7044.118.6.1433 | DOI Listing |
Sci Rep
December 2024
Department of Critical Care Medicine, Heping Hospital Affiliated to Changzhi Medical College, 110 South Yan'an Road, Luzhou District, Changzhi City, 046012, China.
Mechanical ventilation contributes to diaphragm atrophy and muscle weakness, which is referred to as ventilator-induced diaphragmatic dysfunction (VIDD). The pathogenesis of VIDD has not been fully understood until recently. The aim of this study was to investigate the effects of 24 h of mechanical ventilation on fibro-adipogenic progenitor (FAP) proliferation, endothelial-mesenchymal transition (EndMT), and immune cell infiltration driving diaphragm fibrosis in a rabbit model.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
December 2024
Department of Chemistry, COMSATS University, Abbottabad 22060, KPK, Pakistan.
The ruthenium compounds have been known to have the wide range of potential applications as anticancer, antibacterial and anti-diabetic etc. The ligand substitutions play a vital role in enhancing the pharmacological and biological activities. In the present study, three ruthenium-metal based complexes, designated as (I-III), were synthesized and characterized employing element analysis, FTIR and HNMR.
View Article and Find Full Text PDFBraz J Microbiol
December 2024
Institute of Microbiology, Faculty of Veterinary Science, University of Agriculture, Faisalabad, 38040, Pakistan.
Epsilon toxin (ETX) is an exotoxin produced by Clostridium perfringens type D that induces enterotoxaemia or necrotic intestinal infection in small ruminants and bovine. Immunization is an essential element in preventing the spread of infectious diseases. In recent literature, nanocarriers have exhibited the capacity to deliver protection, stability, and regulated distribution properties to protein-based antigens.
View Article and Find Full Text PDFVet Clin North Am Exot Anim Pract
December 2024
Zoological Medicine Service, Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Oklahoma State University, 2065 W. Farm Road, Stillwater, OK 74078, USA. Electronic address:
This article reviews treatment of gastrointestinal (GI) disorders in exotic companion mammal species, birds, reptiles, amphibians, and fish. Treatment of GI stasis involves fluids, nutrition, and analgesia; there is minimal evidence suggesting prokinetics are useful. Research has evaluated the efficacy of various appetite stimulants in several exotic animal species.
View Article and Find Full Text PDFVet Clin North Am Exot Anim Pract
December 2024
Zoological Medicine Service, Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Oklahoma State University, 2065 W. Farm Road, Stillwater, OK 74078, USA. Electronic address:
Antimicrobials should be used judiciously when managing gastrointestinal disorders in exotic animals. Oral administration of antibiotics targeting gram-positive flora must be avoided in hindgut fermenters. Immunosuppressives may be indicated for certain infectious diseases, such as chronic enteric coronavirus in ferrets and avian ganglioneuritis in parrots.
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