Purpose Of Review: The purpose of the review is to provide an update on the safety and efficacy of catheter cryoablation.
Recent Findings: Catheter cryoablation is a safe and clinically effective method for ablation of atrioventricular nodal reentrant supraventricular tachycardia. Although the acute procedural success rate of catheter cryoablation for this arrhythmia may be slightly lower than that reported for radiofrequency ablation, it has an excellent safety profile, with no reported instances of inadvertent atrioventricular block requiring implantation of a permanent pacemaker. Using this technology, one can perform reversible cryomapping, which helps to identify suitable ablation targets while identifying sites where cryoablation should be avoided. For patients with midseptal and parahissian accessory pathways, in whom the risk of producing inadvertent atrioventricular block is substantial, catheter cryoablation is a safe and effective alternative to radiofrequency ablation. Catheter cryoablation of common atrial flutter causes much less patient discomfort than radiofrequency ablation, with excellent acute and long-term efficacy. Catheter cryoablation also can be used to isolate the pulmonary veins during ablation of atrial fibrillation. As compared with radiofrequency ablation, the risk of acute thromboembolic complications and of pulmonary vein stenosis appears to be lower with cryoablation.
Summary: For many cardiac arrhythmias, catheter cryoablation is a safe and effective alternative to radiofrequency ablation. The ability to identify suitable ablation targets by reversible cryomapping is a particularly useful feature of this technology. Although the acute procedural success rate of cryoablation may not equal that of radiofrequency ablation in all circumstances, as catheter technology evolves it is likely that the efficacy of cryoablation will improve and the list of arrhythmias that can be treated with this method will expand.
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J Cardiovasc Dev Dis
December 2024
Department of Cardiology, Rush University Medical Center, Chicago, IL 60612, USA.
Pulsed field ablation (PFA) is a catheter-based procedure that utilizes short high voltage and short-duration electrical field pulses to induce tissue injury. The last decade has yielded significant scientific progress and quickened interest in PFA as an energy modality leading to the emergence of the clinical use of PFA technologies for the treatment of atrial fibrillation. It is generally agreed that more research is needed to improve our biophysical understanding of PFA for clinical cardiac applications as well as its potential as a potential alternative energy source to thermal ablation modalities for the treatment of other arrhythmias.
View Article and Find Full Text PDFCardiol Rev
December 2024
Department of Hospital Medicine, Cheshire Medical Center/Dartmouth Health Keene, NH.
Atrial fibrillation (AF) catheter ablation is safe and effective, though rare cases of takotsubo syndrome (TTS) have been observed without proven causation. This review synthesizes TTS following AF ablation case reports and series. Until October 2024, PubMed/Medline, SCOPUS, and Google Scholar were searched for AF ablation and TTS case reports and series.
View Article and Find Full Text PDFInt J Med Sci
January 2025
Department of Cardiology, The Second Xiangya Hospital, Central South University, Changsha 410011, Hunan Province, People's Republic of China.
The efficacy of radiofrequency ablation (RFA) in patients with atrial fibrillation (AF) and heart failure with preserved ejection fraction (HFpEF) has been established, but the efficacy and safety of cryoballoon ablation (CBA) and pulsed field ablation (PFA) remain unclear. This retrospective cohort study included 223 patients with paroxysmal non-valvular AF and HFpEF who underwent their first AF ablation between January 2017 and December 2021 and were divided into RFA (n = 77), CBA (n = 127), and PFA (n = 19) groups. After a mean follow-up of 11.
View Article and Find Full Text PDFCirc J
January 2025
Department of Cardiovascular Medicine, Faculty of Medical Sciences, University of Fukui.
Catheter ablation is a widely used treatment modality for various cardiac tachyarrhythmias, including atrial and ventricular arrhythmias. Although it is generally considered safe, the procedure carries potential complications, with coronary artery injury being one of the most significant. The aim of this systematic review was to assess the incidence, mechanisms, contributing factors, diagnostic strategies, and preventive measures related to coronary artery injury in patients undergoing catheter ablation, including radiofrequency catheter ablation, cryoablation, and pulsed-field ablation.
View Article and Find Full Text PDFPulsed Field Ablation (PFA) is a new ablation method being rapidly adopted for treatment of atrial fibrillation, which shows advantages in safety and efficiency over radiofrequency and cryo-ablation. In this study, we used an in vivo swine model (10 healthy and 5 with chronic myocardial infarct) for ventricular PFA, collecting intracardiac electrograms, electro-anatomical maps, native T1-weighted and late gadolinium enhancement MRI, gross pathology, and histology. We used 1000-1500 V pulses, with 1-16 pulse trains to vary PFA dose.
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