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Whole lung radiomic features are associated with overall survival in patients with locally advanced non-small cell lung cancer treated with definitive radiotherapy.
Radiat Oncol
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Department of Radiation Oncology, Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, 300060, China.
Background: Several studies have suggested that lung tissue heterogeneity is associated with overall survival (OS) in lung cancer. However, the quantitative relationship between the two remains unknown. The purpose of this study is to investigate the prognostic value of whole lung-based and tumor-based radiomics for OS in LA-NSCLC treated with definitive radiotherapy.
View Article and Find Full Text PDFNasal microbial diversity is associated with survival in piglets infected by a highly virulent PRRSV-1 strain.
Anim Microbiome
January 2025
Department of Animal Health and Anatomy, Universitat Autònoma de Barcelona, Travessera dels Turons s/n, 08193, Cerdanyola del Vallès, Spain.
Background: Porcine reproductive and respiratory syndrome virus (PRRSV) is a major threat to swine industry worldwide, especially virulent variants arising during the last years, such as Spanish PRRSV-1 Rosalia strain. The role of the nasal microbiota in respiratory viral infections is still to be unveiled but may be promisingly related with the health status of the animals and thus, their susceptibility. The goal of this project was to study the nasal microbiota composition of piglets during a highly virulent PRRSV-1 outbreak comparing animals that died due to the infection with animals that survived it.
View Article and Find Full Text PDFImplementing a Responsible Conduct of Research Curriculum for an Undergraduate Summer Clinical Research Program in Quantitative Sciences.
J Med Educ Curric Dev
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Department of Health Policy and Management, Columbia University Mailman School of Public Health, New York, NY, USA.
Objectives: Instilling the principles of ethical and responsible medical research is critical for educating the next generation of clinical researchers. We developed a responsible conduct of research (RCR) workshop and associated curriculum for undergraduate trainees in a quantitative clinical research program.
Methods: Topics in this 7-module RCR workshop are relevant to undergraduate trainees in quantitative fields, many of whom are learning about these concepts for the first time.
Social life cycle assessment of industrial gold mining in Mali.
Integr Environ Assess Manag
January 2025
Department of Agriculture and Environmental Engineering, University of Ibadan, Ibadan, Nigeria.
Gold mining in Mali contributes significantly to the country's socio-economic growth, employing hundreds of people and generating considerable export revenues and income. At the same time, gold mining still has a bad reputation in public opinion due to the environmental and socio-economic challenges it poses. It is therefore important to integrate Mali's gold mining sector into a framework of social responsibility, using the Social Life Cycle Assessment (S-LCA) approach to identify and understand social opportunities and challenges.
View Article and Find Full Text PDFThe value of blood lactate and lactate clearance rate in evaluating the prognosis of athletes with heat illness of varying degrees after high-intensity exercise.
BMC Sports Sci Med Rehabil
January 2025
Department of Pharmacy, The 969 th Hospital of P.L.A, Hohhot, 010051, China.
Background: Heat stroke, a severe heat illness with organ damage, is a major cause of cause irreparable organ damage and higher death rates among military persons and athletes.
Objectives: To study the changes in blood lactate (Lac) levels and lactate clearance rate (LCR) in athletes with heat illness of varying degrees after high-intensity exercise and to evaluate their prognostic value.
Material And Methods: In present study, acute care unit admitted 36 heat sickness patients following high-intensity exercise from December 2019 to July 2024, with comprehensive medical records, for retrospective study.
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