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The association between county-level social determinants of health and cardio-kidney-metabolic disease attributed all-cause mortality in the US: A cross sectional analysis.
Am J Med Sci
January 2025
Case Western Reserve University School of Medicine, Cleveland, USA; Harrington Heart and Vascular Institute, University Hospitals, Cleveland, USA; Louis Stokes Cleveland VA Medical Center, Cleveland, USA. Electronic address:
Background: The American Heart Association recently defined cardio-kidney-metabolic (CKM) syndrome as the intersection between metabolic, renal, and cardiovascular disease. Understanding the contemporary estimates of CKM related mortality in the US is essential for developing targeted public interventions.
Methods: We analyzed state-level and county-level CKM-associated all-cause mortality data (2010-2019) from the CDC Wide-ranging Online Data for Epidemiologic Research (WONDER).
Semaglutide in obesity-related heart failure with preserved ejection fraction and type 2 diabetes across baseline HbA levels (STEP-HFpEF DM): a prespecified analysis of heart failure and metabolic outcomes from a randomised, placebo-controlled trial.
Lancet Diabetes Endocrinol
January 2025
Department of Cardiovascular Disease, Saint Luke's Mid America Heart Institute, University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA. Electronic address:
Background: About half of patients with heart failure with mildly reduced or preserved ejection fraction (HFpEF) have type 2 diabetes. In the STEP-HFpEF DM trial of adults with obesity-related HFpEF and type 2 diabetes, subcutaneous once weekly semaglutide 2·4 mg conferred improvements in heart failure-related symptoms and physical limitations, bodyweight, and other heart failure outcomes. We aimed to determine whether these effects of semaglutide differ according to baseline HbA.
View Article and Find Full Text PDFSimplified Outcome Prediction in Patients Undergoing Transcatheter Tricuspid Valve Intervention by Survival Tree-Based Modelling.
JACC Adv
January 2025
Department of General and Interventional Cardiology, Heart and Diabetes Center North Rhine-Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany. Electronic address:
Background: Patients with severe tricuspid regurgitation (TR) typically present with heterogeneity in the extent of cardiac dysfunction and extra-cardiac comorbidities, which play a decisive role for survival after transcatheter tricuspid valve intervention (TTVI).
Objectives: This aim of this study was to create a survival tree-based model to determine the cardiac and extra-cardiac features associated with 2-year survival after TTVI.
Methods: The study included 918 patients (derivation set, n = 631; validation set, n = 287) undergoing TTVI for severe TR.
Right coronary artery pericoronary fat attenuation index as a future predictor for acute coronary events in nonobstructive coronary artery disease - a prospective single centre study.
Clin Radiol
December 2024
Department of Imaging Sciences and Interventional Radiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, 695011, Kerala, India. Electronic address:
Aim: Evaluation of pericoronary adipose tissue changes induced by inflammation by non-invasive techniques is challenging.
Purpose: To find the association between pericoronary adipose tissue attenuation (FAI) changes and future acute coronary events in nonobstructive coronary artery disease.
Materials And Methods: Ours was a single-centre, prospective observational study on patients with atypical chest pain who underwent coronary computed tomography angiography (CCTA).
Wearable heart rate variability analysis system based on ionic conductive hydrogels.
Talanta
January 2025
Academy of Medical Engineering and Translational Medicine, Medical School, Tianjin University, Tianjin, 300072, China; School of Exercise and Health, Tianjin University of Sport, Tianjin, 300211, China. Electronic address:
Developing a wearable device that can continuously and reliably detect and evaluate heart rate variability (HRV) parameters is critical for the diabetic population with cardiac autonomic neuropathy (CAN). In this work, we proposed a zwitterionic conducting hydrogel that enabled a reliable and comfortable wearable device for the evaluation and detection of the autonomic nervous system (ANS). The hydrogel can achieve a strain of 2003 %, an electrical conductivity of 190 mS/m, and is capable of adhering to a variety of materials, including wood, plastic, and glass.
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