AI Article Synopsis
- The study uses atomic force microscopy to investigate how supported phospholipid bilayers transition from a gel state to a fluid state, focusing on specific phospholipids.
- The primary transition occurs at a temperature known as T(m), marked by the formation of cracks in the gel phase that lead into the fluid phase.
- A secondary phase transition is observed about 5 degrees Celsius above T(m), caused by the separation between the two layers of the bilayer, but this transition can be suppressed by adding a protein or creating defects in the gel phase.
Article Abstract
We utilize in situ, temperature-dependent atomic force microscopy to examine the gel-fluid phase transition behavior in supported phospholipid bilayers constructed from 1,2-dimyristoyl-sn-glycero-3-phosphocholine, 1,2-dipentadecanoyl-sn-glycero-3-phosphocholine, and 1,2-dipalmitoyl-sn-glycero-3-phosphocholine. The primary gel-fluid phase transition at T(m) occurs through development of anisotropic cracks in the gel phase, which develop into the fluid phase. At approximately 5 degrees C above T(m), atomic force microscopy studies reveal the presence of a secondary phase transition in all three bilayers studied. The secondary phase transition occurs as a consequence of decoupling between the two leaflets of the bilayer due to enhanced stabilization of the lower leaflet with either the support or the water entrained between the support and the bilayer. Addition of the transmembrane protein gramicidin A or construction of a highly defected gel phase results in elimination of this decoupling and removal of the secondary phase transition.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1305267 | PMC |
| http://dx.doi.org/10.1529/biophysj.104.052456 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Multiple Magnetic Phase Transitions and Giant Refrigerant Capacity in a GdDyHoErTm High-Entropy Alloy.
ACS Appl Mater Interfaces
December 2024
School of Materials Science and Engineering, Nanjing University of Science and Technology, Nanjing 210094, China.
Magnetocaloric high-entropy alloys (HEAs) have recently garnered significant interest owing to their potential applications in magnetic refrigeration, offering a wide working temperature range and large refrigerant capacity. In this study, we thoroughly investigated the structural, magnetic, and magnetocaloric properties of equiatomic GdDyHoErTm HEAs. The as-cast alloy exhibits a single hexagonal phase, a randomly distributed grain orientation, and complex magnetism.
View Article and Find Full Text PDFHigh-Throughput Exploration of Ti-V-Nb-Mo Carbide MXenes Using Neural Network Potentials and Their Evaluation as Catalysts for Hydrogen Evolution Reaction.
ACS Appl Mater Interfaces
December 2024
TCS Research, Sahyadri Park 2, Rajiv Gandhi Infotech Park, Hinjewadi Phase 3, Pune 411057, India.
Realization of a sustainable hydrogen economy in the future requires the development of efficient and cost-effective catalysts for its production at scale. MXenes (MX) are a class of 2D materials with 'n' layers of carbon or nitrogen (X) interleaved by 'n+1' layers of transition metal (M) and have emerged as promising materials for various applications including catalysts for hydrogen evolution reaction (HER). Their properties are intimately related to both their composition and their atomic structure.
View Article and Find Full Text PDFExploring therapeutic alliance in spinal cord injury rehabilitation: Control, identity, and liminality.
Physiother Theory Pract
December 2024
Queensland University of Technology, Kelvin Grove, Australia.
Background: The therapeutic alliance (TA) has emerged as a key principle in enhancing the quality of health and rehabilitation services.
Purpose: This study aimed to explore patient perspectives on the influence of TAs with practitioners during inpatient rehabilitation following spinal cord injury (SCI).
Methods: Using a qualitative methodology, ( = 18) in-depth interviews were conducted with inpatient participants.
Curdlan inclusion modifies the rheological properties and the helix-coil transition behavior of gelatin and increases the flexibility of gelatin films.
Food Chem
December 2024
College of Food Science and Engineering, Qingdao Agricultural University, Qingdao, Shandong 266109, China; School of Light Industry, Beijing Technology & Business University (BTBU), Beijing 100048, China; Shandong Ensign Industry Co., Ltd., Weifang, Shandong 262409, China. Electronic address:
Gelatin, a natural and edible polymer, has attracted wide attention for use in food and edible packaging applications. However, its inadequate properties, especially poor flexibility, limit its broader utilization. Hybridizing different polymers is a promising strategy to achieve enhanced properties.
View Article and Find Full Text PDFInvestigations on the Origin of Topotactic Phase Transition of LaCoO Thin Films with In Situ XRD and Ambient Pressure Hard X-ray Photoelectron Spectroscopy.
ACS Appl Mater Interfaces
December 2024
Department of Materials Science and Engineering, Chosun University, Gwangju 61452, Korea.
With the applications of in situ X-ray diffraction (XRD), electrical - measurement, and ambient pressure hard X-ray photoelectron spectroscopy (AP-HAXPES), the characteristics of the topotactic phase transition of LaCoO (LCO) thin films are examined. XRD measurements show clear evidence of structural phase transition (SPT) of the LCO thin films from the perovskite (PV) LaCoO to the brownmillerite (BM) LaCoO phases through the intermediate LaCoO phase at a temperature of 350 °C under high-vacuum conditions, ∼10 mbar. The reverse SPT from BM to PV phases is also found under ambient pressure (>100 mbar) of air near 100 °C.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!