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Dipteran-specific Daedalus controls Zucchini endonucleolysis in piRNA biogenesis independent of exonucleases.

Cell Rep

November 2024

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo 113-0032, Japan. Electronic address:

PIWI-interacting RNAs (piRNAs) protect germline genomes and maintain fertility by repressing transposons. Daedalus and Gasz act together as a mitochondrial scaffold for Armitage, a necessary factor for Zucchini-dependent piRNA processing. However, the mechanism underlying this function remains unclear.

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Objective: To explore the potential adverse effects of prolonged inhalation of mosquito coil smoke on the testicular histomorphology and serum testosterone levels in rats.

Study Design: An experimental study. Place and Duration of the Study: Department of Anatomy, Army Medical College, National University of Medical Sciences (NUMS), Rawalpindi, Pakistan, from January to December 2020.

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Determination of personal exposure to volatile organic compounds and their health risks after the use of mosquito repellents in residential environments using passive sampling.

Sci Total Environ

November 2024

Division of Environmental Science and Ecological Engineering, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Republic of Korea. Electronic address:

Article Synopsis
  • Mosquito repellents commonly used in Asia, Africa, and South America release indoor volatile organic compounds (VOCs), which can affect human health.
  • The study examined the emission characteristics of three repellent types—coils, mats, and liquids—using real-time measurement and a personal passive sampler over 3 hours of typical use by 86 volunteers.
  • Significant increases in indoor benzene levels were linked to coil and mat repellents, while liquid repellents increased α-pinene; the cancer risk from benzene for users of coil and mat repellents was notable, prompting the need for more research on the health impacts of these products.
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Article Synopsis
  • The study aimed to assess the protective effects of coenzyme Q10 (CoQ10) on the testicular health of rats exposed to smoke from mosquito coils over a 12-week period.
  • Thirty male Sprague Dawley rats were divided into three groups: a control group, a group exposed only to mosquito coil smoke, and a group exposed to the smoke while receiving CoQ10.
  • Results indicated that exposure to the smoke caused significant testicular damage in the rats, while those receiving CoQ10 showed no significant changes in testicular histology, suggesting that CoQ10 could prevent harm from the smoke.
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Background: Microsensors have been used for the high-resolution particulate matter (PM) monitoring.

Objectives: This study applies PM and health microsensors with the objective of assessing the peak exposure, sources, and immediate health impacts of PM and PM in two Asian countries.

Methods: Exposure assessment and health evaluation were carried out for 50 subjects in 2018 and 2019 in Bandung, Indonesia and for 55 subjects in 2019 and 2020 in Kaohsiung, Taiwan.

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