Objective: To examine the expression of molecules targeted by imatinib mesylate (STI571;Gleevec) and epidermal growth factor receptor (EGFR) inhibitors in orbital lymphangiomas.
Design: Retrospective observational case series.
Participants: Six patients with orbital lymphangioma treated at four institutions between March 2000 and December 2002.
Methods: Tissue specimens and medical records from six patients were collected. Immunohistochemical analysis was performed using antibodies against c-kit and platelet-derived growth factor receptor (PDGFR) alpha and beta and EGFR tyrosine kinase.
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| http://dx.doi.org/10.1080/01676830590889875 | DOI Listing |
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