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Dextrocardia is a very rare congenital malposition, and most cardiologists are not familiar with the radiographic angiograms of this condition. Here, we first report a case of dextrocardia with a chronic total occlusion (CTO) lesion undergoing retrograde percutaneous coronary intervention (PCI). Significant difficulties in lesion interpretation and device manipulation were encountered with the original angiograms.
View Article and Find Full Text PDFHuman Genetics of Defects of Situs.
Adv Exp Med Biol
June 2024
Cardiovascular Genetics, Charité Universitätsmedizin Berlin, Berlin, Germany.
Article Synopsis
- Defects of situs are linked to various congenital heart conditions where the usual positioning of thoracic and abdominal organs is disrupted.
- Recent research has discovered mutations in at least 33 different genes in people with these defects, affecting diverse molecular components like transcription factors and ciliary proteins.
- There is significant overlap between genes involved in situs defects and those associated with other congenital heart diseases, highlighting the genetic complexity of these conditions.
Clinical implications of dextrocardia based on four visceroatrial situs studies.
Pediatr Neonatol
November 2024
Department of Pediatrics, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan. Electronic address:
Background: Previous studies on congenital heart diseases (CHD) associated with dextrocardia were based on selective patient databases and did not reflect the full spectrum of dextrocardia in the general population. Additionally, these studies had complex classification and presentation. Nor did these studies elaborate on the distribution of the associated CHD's complexity, the various segmental connections, and associated CHD among the four visceroatrial situs.
View Article and Find Full Text PDFAtrial tachycardia ablation through the sub-pulmonary ventricle in a patient with multiple malformations associated with congenitally corrected transposition of the great arteries and double-sided slow-pathway.
Clin Case Rep
April 2024
Cardio-Thoraco-Vascular Department, Electrophysiology Unit ASST Grande Ospedale Metropolitano Niguarda Milan Italy.
A 46-year-old woman with congenitally corrected transposition of the great arteries (ccTGA) associated with dextrocardia, situs viscerus inversus, and left superior vena cava persistence presented with an incessant supraventricular tachycardia. Electrophysiological study was not conclusive in differential diagnosis of atrial tachycardia versus atypical atrioventricular (AV) nodal reentrant tachycardia, also due to the unconventional anatomy of the coronary sinus. By a comprehensive mapping of cardiac chambers, a double side slow-pathway was localized in both atrial chambers and subsequently ablated by radiofrequency delivery without tachycardia changes.
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