We report an immunocompromised woman with chronic lymphocytic leukemia who developed cutaneous zygomycosis at the site of an arterial line. The initial lesion resembled a bulls-eye. Bull's-eye lesions of zygomycosis have been reported twice before. Recognition of this sign may allow the dermatologist to make a rapid presumptive diagnosis and initiate treatment for this life-threatening infection.
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| http://dx.doi.org/10.1016/j.jaad.2004.07.027 | DOI Listing |
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- Hydroxychloroquine (HCQ) is commonly used to treat autoimmune diseases like rheumatoid arthritis and systemic lupus erythematosus but can lead to serious side effects, such as skin hyperpigmentation and eye damage.
- A case study highlighted a 65-year-old woman who developed blurred vision and hyperpigmentation after three years on HCQ for rheumatoid arthritis, leading to a diagnosis of drug-induced skin pigmentation and macular lesions.
- Following the discontinuation of HCQ and switching to iguratimod treatment, her skin pigmentation improved, although her vision issues persisted, stressing the importance of monitoring and regular eye exams for patients on HCQ.
Merging Patches, an Atypical Presentation of Disseminated Cutaneous Lyme Disease: A Case Report.
J Emerg Med
December 2020
Department of Emergency Medicine, University Health Network, Toronto, Ontario, Canada; Stadium Medicine, Toronto Blue Jays, Toronto, Ontario, Canada.
Background: Lyme disease, spread by the Ixodes tick, is typically associated with a single "bull's eye rash" that emergency physicians are comfortable recognizing and treating during the summer months when this disease is most prevalent. However, Lyme disease can also present in disseminated forms that are more difficult to diagnose.
Case Report: We describe a phenomenon of disseminated Lyme with multiple rash complexes that is unrecognized by clinicians.
Vesicular erythema migrans: an atypical and easily misdiagnosed form of Lyme disease.
Dermatol Online J
August 2015
The Ronald O. Perelman Department of Dermatology, New York University School of Medicine.
Erythema migrans is the initial sign in the majority of patients infected with Borrelia, the genus of spirochetes that causes Lyme disease. Early identification and treatment decrease the risk of progression to later stages of disease. Although a "bull's eye" appearance owing to lesional clearing is considered classic for erythema migrans, this feature is surprisingly often lacking among patients in the United States.
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