Azithromycin retards Pseudomonas aeruginosa biofilm formation.

J Clin Microbiol

Department of Microbiology and Immunology, Box 672, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA.

Published: December 2004

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Article Abstract

Using a flow cell biofilm model, we showed that a sub-MIC of azithromycin (AZM) can delay but not inhibit Pseudomonas aeruginosa biofilm formation and results in the development of a stable AZM resistance phenotype. Furthermore, mature biofilms were not affected by AZM.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC535287PMC
http://dx.doi.org/10.1128/JCM.42.12.5842-5845.2004DOI Listing

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