Using a flow cell biofilm model, we showed that a sub-MIC of azithromycin (AZM) can delay but not inhibit Pseudomonas aeruginosa biofilm formation and results in the development of a stable AZM resistance phenotype. Furthermore, mature biofilms were not affected by AZM.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC535287 | PMC |
http://dx.doi.org/10.1128/JCM.42.12.5842-5845.2004 | DOI Listing |
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