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Toxocariasis and Strongyloidiasis as Triggering Factors for Wells' Syndrome.

Clin Cosmet Investig Dermatol

July 2024

Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran, Dr. Hasan Sadikin Hospital, Bandung, Indonesia.

Article Synopsis
  • Wells' syndrome is a rare skin condition marked by itchy, red lesions and swelling, often linked to high eosinophil levels and sometimes triggered by parasitic infections.
  • A case study in Indonesia reports a 27-year-old male who experienced recurrent painful rashes, fever, and diarrhea, ultimately diagnosed with Wells' syndrome after identifying eosinophilia and conducting histopathological tests.
  • The patient was treated for strongyloidiasis with albendazole, leading to improvement within two weeks, highlighting the importance of accurate diagnosis through clinical and pathological evaluations.
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Article Synopsis
  • The study compared two diagnostic methods, semi-nested PCR and indirect ELISA, for detecting human fasciolosis using 70 serum samples from suspected patients in Iran.
  • Results showed that semi-nested PCR had a higher agreement rate (98.4%) compared to indirect ELISA (94.46%), with no false positives from other parasitic infections.
  • The findings suggest that semi-nested PCR is a reliable confirmatory method and can be used to monitor patient treatment effectively.
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Background: Human toxocariasis is a neglected parasitic disease in most countries including Iran. Among different clinical forms of toxocariasis, ocular toxocariasis (OT) is an important disease resulting in severe vision loss. However, the prevalence and incidence of OT are currently unclear in Iran.

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Objectives: Human toxocariasis is a widespread zoonosis for which a chemotherapy decision and therapy effectiveness are difficult to determine. We aimed to investigate the kinetic profile of clinical and laboratory findings and treatment outcome of patients with toxocariasis in Vietnam.

Methods: The prospective study was conducted between October 2017 and June 2019.

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Toxocariosis is a parasitic disease caused by the larvae from genus Toxocara sp. There are two classic syndromes described for this entity: visceral larva migrans and ocular larva migrans, depending on larvae localization. Human being behaves as an accidental host in which Toxocara sp.

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