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Genetic etiology of Perrault syndrome in Iranian families: first report from Iran and literature review.
J Appl Genet
January 2025
Genetics Research Center, University of Social Welfare and Rehabilitation Sciences, Koodakyar Avenue, Daneshjoo Blvd, Evin, Tehran, 1985713834, Iran.
Perrault syndrome (PS) is an extremely rare autosomal recessive condition characterized primarily by bilateral sensorineural hearing loss in both genders and primary or secondary ovarian failure in females. Neurological features such as cerebral ataxia, peripheral neuropathy, epilepsy, and intellectual disability are frequent manifestations of PS. To date, six genes have been reported to cause PS, and nearly 100 families have been identified worldwide with this syndrome.
View Article and Find Full Text PDFCost-effectiveness of hearing aids in South Korea: a multistate Markov model analysis.
Clin Exp Otorhinolaryngol
January 2025
Department of Medicine, College of Medicine, Seoul National University, Seoul, South Korea.
Objectives: This study evaluated the cost-effectiveness of using hearing aids among individuals aged 50 and older with varying levels of hearing loss in South Korea.
Methods: A state-transition Markov model was employed to assess the cost-effectiveness of hearing aid utilization from a societal perspective. We simulated a cohort of patients aged 50, tracking their progression through normal, mild, moderate, and severe stages of hearing loss until death or age 80.
Efficacy of virtual reality pure-tone audiometry in training of hearing test for audiologist.
Heliyon
December 2024
Department of Otorhinolaryngology, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea.
Background And Objectives: The immersive virtual reality (VR) simulator is advantageous because it is cost-effective, realistic, can be controlled directly by the user, and can be integrated into education and training in otorhinolaryngology. The present study explored the feasibility of incorporating VR pure-tone audiometry (PTA) into an audiologist training curriculum, and assessed audiology experts' willingness to use a VR PTA.
Materials And Methods: A total of 31 audiologists (16 skilled audiologists and 15 undergraduate students) participated in the study, using a developed VR PTA application with a Meta Quest 2 device.
Hearing the unheard: Fundamentals of acoustic emission signals as predictors of total hip arthroplasty implant loosening.
Med Eng Phys
December 2024
Laboratory for Biomechanics and Biomaterials (LBB), Department of Orthopaedic Surgery, Hannover Medical School, Anna-von-Borries-Strasse 1-7, 30625 Hannover, Germany. Electronic address:
Implant loosening remains a primary cause of failure of total hip arthroplasty (THA) and is often detected late, when pain occurs. Acoustic emission (AE) analysis is a promising method for early loosening detection, on the supposition that relative movements at the bone-implant interface induce detectable AE signals. To distinguish loosening-induced AE signals from those of stable THA components in vitro investigations are necessary.
View Article and Find Full Text PDFDevelopment and verification of non-supervised smartphone-based methods for assessing pure-tone thresholds and loudness perception.
Int J Audiol
December 2024
Medizinische Physik and Cluster of Excellence Hearing4all, Universität Oldenburg, Oldenburg, Germany.
Objective: The benefit of using smartphones for hearing tests in a non-supervised, rapid, and contactless way has drawn a lot of interest, especially if supra-threshold measures are assessed that go beyond audiogram-based measures alone. It is unclear, nevertheless, how well these measures compare to more supervised and regulated manual audiometric assessments. The aim of this study is to validate such smartphone-based methods against standardised laboratory assessments.
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