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Aim To evaluate the effect of bromocriptine on clinical hemodynamic and functional indexes and to analyze life prognosis for patients with periportal cardiomyopathy divided into two groups: group 1, bromocriptine treatment (n=21) and group 2, standard treatment without bromocriptine (n=22). History was taken, examination and standard clinical evaluation were performed, the Clinical Condition Scale (CCS with V.Yu.
View Article and Find Full Text PDFEndomyocardial fibrosis (EMF) in a Ugandan child with advanced hepatosplenic schistosomiasis: coincidence or connection?
Am J Trop Med Hyg
October 2014
Department of Parasitology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom; Department of Pediatrics, Guy's and St. Thomas's National Health Service (NHS) Trust, London, United Kingdom; Department of Internal Medicine, Mulago Hospital, Kampala, Uganda; Department of Radiology, Mulago Hospital, Kampala, Uganda; Hospital for Tropical Diseases, Mortimer Market Centre, London, United Kingdom; Department of Infection, Guy's and St. Thomas's NHS Trust, London, United Kingdom.
An association between late-stage hepatosplenic schistosomiasis and endomyocardial fibrosis (EMF) has been suggested but not proven. We present the case of a 12-year-old Ugandan boy with striking comorbidities, including advanced periportal fibrosis caused by Schistosoma mansoni infection and right ventricular EMF, and discuss the possible correlation between both diseases.
View Article and Find Full Text PDFResults of the study of special characteristics of the course of chronic heart failure (CHF) in women with periportal cardiomyopathy (PCMP) are presented. We have found that prevalence of PCMP in the structure of dilated cardiomyopathy is 9.5%.
View Article and Find Full Text PDFEndomyocardial fibrosis associated with mansoni schistosomiasis.
Rev Soc Bras Med Trop
October 2011
Departamento de Clínica Médica, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Endomyocardial fibrosis (EMF) is a neglected tropical disease that affects millions of people worldwide. EMF is the most common cause of restrictive cardiomyopathy, caused by deposition of fibrous tissue on endocardial surfaces. EMF is a major cause of death in areas where it is endemic, but the pathogenesis of the disease is poorly understood.
View Article and Find Full Text PDFA Taiwanese boy with congenital generalized lipodystrophy caused by homozygous Ile262fs mutation in the BSCL2 gene.
Kaohsiung J Med Sci
November 2010
Department of Family Medicine, Kaohsiung Medical University Hospital, Taiwan.
Congenital generalized lipodystrophy (CGL) is a rare autosomal recessive disease that is characterized by a near-complete absence of adipose tissue from birth or early infancy. Mutations in the BSCL2 gene are known to result in CGL2, a more severe phenotype than CGL1, with earlier onset, more extensive fat loss and biochemical changes, more severe intellectual impairment, and more severe cardiomyopathy. We report a 3-month-old Taiwanese boy with initial presentation of a lack of subcutaneous fat, prominent musculature, generalized eruptive xanthomas, and extreme hypertriglyceridemia.
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