In honour of the retirement of our director Margaret Burgess, National Centre for Immunisation Research and Surveillance (NCIRS) held a Festschrift on 5th to 6th February 2004. The themes of the event were Vaccines for the 21st Century and Congenital and Neonatal Infections. International guests attended the Festschrift, as well as over 180 colleagues and co-workers from across Australia. A summary of the presentations over these two fascinating days is provided herein.
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Vaccine
March 2019
National Centre for Immunisation Research and Surveillance. Locked bag 4001, Westmead, Sydney 2145, Australia.
BMC Infect Dis
February 2019
Department of Experimental Virology, University Hospital Jena, Jena, Germany.
Background: A controversy exists about the potential effect of childhood varicella vaccination on Herpes Zoster (HZ) incidence. Mathematical models projected temporary HZ incidence increase after vaccine introduction that was not confirmed by real-world evidence. These models assume that absence of contacts with infected children would prevent exogenous boosting of Varicella-Zoster-Virus (VZV) immunity and they do not include an endogenous VZV immunity-boosting mechanism following asymptomatic VZV reactivation.
View Article and Find Full Text PDFExpert Rev Vaccines
August 2017
f Global Medical Affairs Rota & MMRV, GSK , Wavre , Belgium.
Varicella, although a frequently benign childhood disease, nevertheless represents a considerable health burden. WHO recommends including varicella vaccines in universal routine vaccination programs, and maintaining coverage >80%. Many countries have successfully introduced varicella vaccination and have benefited from lower disease burden, but many others have not adopted the vaccine.
View Article and Find Full Text PDFN S W Public Health Bull
December 2012
National Centre for Immunisation Research and Surveillance, The Children's Hospital at Westmead.
Vaccine
January 2013
School of Public Health and Community Medicine, University of New South Wales, Sydney, NSW 2052, Australia.
We investigated the impact of vaccination on rubella epidemiology in Australia, using a mathematical model fitted to Australian serosurvey data and incorporating pre-vaccination European estimates of rubella transmissibility. Mass infant measles-mumps-rubella (MMR) vaccination produced a 99% reduction in both rubella and congenital rubella syndrome (CRS) incidence by 2010 compared to the pre-vaccination era (1960-70). The model is consistent with reductions in CRS based on surveillance of congenital hearing impairment.
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