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South Asia has high prevalence rates of type 2 diabetes (T2D). Until the 1990s, the prevalence of T2D within South Asia was low but much higher in the South Asian diaspora living abroad. Today, high prevalence rates of T2D are reported among those living in South Asia.
View Article and Find Full Text PDFStandardized pipelines support and facilitate integration of diverse datasets at the Rat Genome Database.
Database (Oxford)
January 2025
Rat Genome Database, Department of Physiology, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, United States.
The Rat Genome Database (RGD) is a multispecies knowledgebase which integrates genetic, multiomic, phenotypic, and disease data across 10 mammalian species. To support cross-species, multiomics studies and to enhance and expand on data manually extracted from the biomedical literature by the RGD team of expert curators, RGD imports and integrates data from multiple sources. These include major databases and a substantial number of domain-specific resources, as well as direct submissions by individual researchers.
View Article and Find Full Text PDFFrom Bedside to Boardroom: Dr. Erik Martin's Unexpected Leadership Journey.
J Nurs Adm
February 2025
Author Affiliations: Vice President, Learning and Development, Indiana University Health, Indianapolis; Social Media Editor, Journal of Nursing Administration, Philadelphia, Pennsylvania.
This interview explores the unexpected leadership journey of Dr Erik Martin, the 2022-2023 American Organization for Nursing Leadership President and chief nursing officer at Norton Children's Hospital. Starting as a bedside nurse, Dr Martin shares how others encouraged him to pursue leadership roles. The interview highlights the turning points in his career, the challenges he has faced, and valuable lessons learned.
View Article and Find Full Text PDFReflecting on partnerships established and sustained over four cycles of a federally funded cancer prevention and control research program: lessons learned for community-academic networks.
Front Public Health
January 2025
Department of Health Promotion, Education, and Behavior, Arnold School of Public Health, University of South Carolina, Columbia, SC, United States.
Introduction: The Centers for Disease Control and Prevention (CDC) funded Cancer Prevention and Control Research Network (CPCRN) is a national network which aims to accelerate the adoption and implementation of evidence-based cancer prevention and control strategies and interventions in communities, enhance large-scale efforts to reach underserved populations and reduce their cancer-related health disparities, and develop the capacity of the dissemination and implementation work force specifically in cancer prevention and control.
Methods: Our site has been a part of the CPCRN since its inception in 2002 with the exception of the 2004-2009 funding cycle. As community-based participatory research is a core value of our center, we examined the development and continued engagement of our community partners using a qualitative, inductive approach to identify emergent themes from focus group sessions with current and past investigators.
Diagnostic delay in cerebral creatine deficiency disorders: lessons learned from a cross-sectional single center study, and guanidinoacetate and creatine measurements in Switzerland between 2015 and 2023.
Mol Cell Pediatr
January 2025
Division of Metabolism and Children`s Research Center, University Children's Hospital Zurich, Lenggstr. 30, 8008, Zurich, Switzerland.
Background: Cerebral creatine deficiency disorders (CCDD) are rare diseases caused by defects in the enzymes L-arginine: glycine amidinotransferase (AGAT) or guanidinoacetate-N-methyltransferase (GAMT), which are involved in synthesis of creatine; or by a defect in the creatine transporter (CRTR), which is essential for uptake of creatine as important energy source into the target cells. Patients with CCDD can present with a variety of unspecific symptoms: global developmental delay, speech-language disorder, behavioral abnormalities and seizures. Early treatment initiation is essential in AGAT and GAMT deficiencies to achieve a favorable outcome.
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